Pursuit of Discovery featuring Dr. Jared Brown

Pursuit of Discovery
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About Dr. Brown's Research

Nanotechnology, the study of manipulating matter on an atomic and molecular scale, is a field that has been steadily growing in the last 10-20 years. Dr. Jared Brown, assistant professor in the Department of Pharmacology and Toxicology, and the researchers in his lab here at East Carolina University have been researching the potential impact of these nanomaterials, especially in understanding what impact exposure to nanoparticles may have on human health. Dr. Brown first became interested in nanotechnology when he was in graduate school at the University of Montana, where there were environmental exposure concerns from different mining operations and asbestos exposure.

Dr. Brown’s recent research suggests that the activation of mast cells is an important step in the initiation and progression of pulmonary inflammation, fibrosis, and cardiovascular injury following exposure to nanoparticles. He has discovered that understanding mast cells is vital to comprehending the full impact of nanomaterials. For the next step in his research, Brown is looking at how to design nanomaterials to make them safe. If he can understand what properties make the nanomaterials toxic, he can modify those properties to make them safe.

The research in nanomaterials Brown is doing at ECU is not only important to the university, but to the whole world. Understanding how the materials actually impact human health is a concern that everyone shares.

This has been a production of East Carolina University. To hear more, please visit www.ecu.edu/pursuitofdiscovery.