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Winners of the five Leo W. Jenkins Cancer Center grants to support research focused on oncology are (left to right) Brian Love, Chemistry; Doug Weidner, Microbiology and Immunology; Fred Bertrand, Microbiology and Immunology; Brett Keiper, Biochemistry and Molecular Biology; Mary Farwell, Biology; Brian Shewchuk, Biochemistry and Molecular Biology; Larry Dobbs, Pathology. (Contributed photo)

Jenkins Center Awards Cancer Research Grants

By Nancy McGillicuddy

The Leo W. Jenkins Cancer Center awarded five grants to support oncology-focused research.

Through the performance of the proposed studies the investigators are expected to accumulate data that will support submission of major grant applications.

Winners were Brian Love, Department of Chemistry; Doug Weidner, Department of Microbiology and Immunology; Fred Bertrand, Microbiology and Immunology; Brett Keiper, Department of Biochemistry and Molecular Biology; Mary Farwell, Department of Biology; Brian Shewchuk, Department of Biochemistry and Molecular Biology; and Larry Dobbs, Department of Pathology.

The winners were selected to research the following:

Fred Bertrand and Doug Weidner, both of the Department of Microbiology and Immunology, were awarded $30,000 to study tumor stem cells in breast and prostate cancer.

Larry Dobbs, Department of Pathology, was awarded $26,000 to research variants in cervical biopsy specimens from patient’s with cervical dysplasia and squamous cell carcinoma.

Brett Keiper, Department of Biochemistry, and Dr. Mary Farewell, Department of Biology, were awarded $35,000 to study targeted depletion of certain isoforms in breast cancer cells lines to reduce proliferation and increase susceptibility to apoptosis.

Brian Schewchuk, Department of Biochemistry, received $35,000 to research modification of the growth hormone locus in breast cancer cell proliferation.

Brian Love, Department of Chemistry, received $12,000 to research synthesis of oxygenated-carboline derivatives as potential anti-cancer agents.

10/10/05
This page originally appeared in the Feb. 3, 2006 issue of Pieces of Eight. Complete issue is archived at http://www.ecu.edu/news/poe/archives.cfm.