DNA Damage and Repair Laboratory

Welcome to the ECU Biology DNA Damage and Repair Laboratory.  Our laboratory was the first internationally to verify the existence of DNA damage clusters in mouse or human tumor tissues. The members of our lab are:

Dr. Alexandros Georgakilas                              

Graduate Students

Thomas Kryston, MSc Candidate
Nicholas Ferguson, MSc Candidate

Christina Burchette, MSc Candidate

Undergraduate Students

Anastassiya Georgiev

Dan Tran

The techniques, methods, and tools we are using for the detection of different types of DNA damage in human cells or tissues are:

1. Pulsed Field Gel Electrophoresis (CHEF Biorad DRII)
2. Neutral and Alkaline Comet Assay
3. Western Blotting
4. Standard Agarose Gel Electrophoresis
5. Image Analysis
6. Enzymatic or chemical probes like human or E.coli repair enzymes or polyamines