Department of Biology

Capehart, Anthony A.

Name:	Dr. Anthony A. Capehart
Title:	Associate Professor
Area of Study:	Developmental Biology
Phone:	252-328-6296
Fax:	252- 328-4178
E-mail:	capehartt@ecu.edu
Office:	Howell Science C-407
Address:	Department of Biology
	East Carolina University
	Greenville, NC 27858

Tony Capehart

Professional Positions
1994-1997     Research Associate, Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC
1997-1999     Research Assistant Professor, Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC
1999-2005         Assistant Professor, Department of Biology, East Carolina University, Greenville, NC
2005-present Associate Professor, Department of Biology, East Carolina University, Greenville, NC

Professional Memberships
North Carolina Academy of Science
Sigma Xi
Society for Developmental Biology

Awards
1987-1988 Department of Biological Sciences Competitive Research Fellowship, University of North Carolina, Wilmington
1988-1989 Dean's Fellowship, Bowman Gray School of Medicine, Wake Forest University
1991-1993 National Institutes of Health National Research Service Award

Selected peer-reviewed publications

1. Capehart, AA and CT Hackney. 1989. The potential role of roots and rhizomes in structuring
salt marsh benthic communities. Estuaries 12: 119-122.

2. Capehart, AA, DM Biddulph, MM Dozier, and NC Julian. 1990. Responsiveness of
adenylate cyclase to PGE2 and forskolin in isolated cells from micromass cultures of
chick limb mesenchyme during chondrogenesis. Prostaglandins 39:167-178.

3. Capehart, AA and DM Biddulph. 1991. Development of PTH-responsive adenylate cyclase activity during chondrogenesis in cultured mesenchyme from chick limb buds. Calcif.Tissue Int. 48: 400-406.

4. Capehart, AA and DM Biddulph. 1991. Effects of a putative prostaglandin E2 antagonist, AH6809, on chondrogenesis in serum-free cultures of chick limb mesenchyme. J. Cell Physiol. 147: 403-411.

5. Biddulph, DM, AA Capehart, and TC Beasley. 1991. Comparative effects of cytosine arabinoside and a prostaglandin E2 antagonist, AH6809, on chondrogenesis in serum-free cultures of chick limb mesenchyme. Exp. Cell Res. 196: 131-133.

6. Capehart, AA, RM Dillaman, and TA Ballard. 1992. Use of rhodamine 123 to identify viable cells isolated from embryonic chick calvaria. J. Tissue Cult. Meth. 14: 79-84.

7. Krug, EL, M Reazee, K Isokawa, DK Turner, LL Litke, AM Wunsch, JL Bain, DA Riley, AA Capehart, and RR Markwald. 1995. Transformation of cardiac endothelium into cushion mesenchyme is dependent upon ES/130: temporal, spatial, and functional studies in the early chick embryo. Cell Mol. Biol. Res. 41: 263-277.

8. Capehart, AA, MM Wienecke, GT Kitten, M Solursh, and EL Krug. 1997. Production of a monoclonal antibody by in vitro immunization that recognizes a native chondroitin sulfate epitope in the embryonic chick limb and heart. J. Histochem. Cytochem. 45: 1567-1581.

9. Capehart, AA and DM Biddulph. 1997. Changes in adenylate cyclase activity during chondrogenesis in chick limb mesenchyme. Meth. Cell Science 19: 121-127.

10. Mjaatvedt, CH, H Yamamura, AA Capehart, D Turner, and RR Markwald. 1998. The Cspg2 gene, disrupted in the hdf mutant, is required for right cardiac chamber and endocardial cushion formation. Dev. Biol. 202: 56-66.

11. Capehart, AA, CH Mjaatvedt, S Hoffman, and EL Krug. 1999. Dynamic expression of a native chondroitin sulfate epitope reveals microheterogeneity of extracellular matrix organization in the embryonic chick heart. Anat. Rec. 254: 181-195.

12. Bianchi, LM, H Liu, EL Krug, and AA Capehart. 1999. Selective and transient expression of a native chondroitin sulfate epitope in Dieter’s cells, pillar cells, and the developing tectorial membrane. Anat. Rec. 256: 64-71.

13. Biddulph, DM, MM Dozier, and AA Capehart. 2000. Inhibition of prostaglandin synthesis reduces cyclic AMP levels and inhibits chondrogenesis in cultured chick limb mesenchyme. Meth. Cell Science 22: 9-16.

14. Capehart, AA. 2001. In vitro production of monoclonal antibodies to cultured embryonic chick limb mesenchyme. Meth. Cell Sci. 22: 319-327.

15. Capehart, AA, J-L Scemama, CA Singhas, and S. Cox. 2002. Heterogeneity of chondroitin sulfate glycosaminoglycan distribution during early development of the striped bass (Morone saxatilis). Anat. Rec. 268: 47-58.

16. Capehart, AA, A Giaimo, and CA Singhas. 2003. Distribution of chondroitin sulfate glycosaminoglycans in the human chorio-amnionic membrane complex at term. J. N.C. Acad. of Science 119:1-12.

17. Capehart, AA and CB Kern. 2003. Identification of gamma A-like protocadherin expressed during chick development. J. Cell. Biochem. 90:608-618.

18. Gillotte, DM, PL Fox, CH Mjaatvedt, S Hoffman, and AA Capehart. 2003. An in vitro method for analysis of chondrogenesis in limb mesenchyme from individual transgenic (hdf) embryos. Meth. Cell Sci. 25: 97-104.

19. Snow, HE, LM Riccio, CH Mjaatvedt, S Hoffman, and AA Capehart. 2005. Versican expression during skeletal/joint morphogenesis and patterning of muscle and nerve in the embryonic mouse limb. Anat. Rec. 282A: 95-105.

20. Williams, DR, AR Presar, AT Richmond, CH Mjaatvedt, S Hoffman, and AA Capehart. 2005. Limb chondrogenesis is compromised in the versican deficient hdf mouse. Biochem. Biophys. Res. Comm. 334: 960-966.

21. Richmond, AT, J Atwood, J Bream, CH Mjaatvedt, S Hoffman, and AA Capehart. 2004 (publ. 2005). Neural tissue co-culture with mesenchyme to investigate patterning of peripheral nerve during murine embryonic development. Cytotechnology 46: 173-182.

22. Cronin, KD and AA Capehart. 2007. Gamma protocadherin expression in the embryonic chick nervous system. Int. J. Biol. Sci. 3: 8-11.

23. Shepard JB, HA Krug, BA LaFoon, S Hoffman and AA Capehart. 2007. Versican expression during synovial joint morphogenesis. Int. J. Biol. Sci. 3: 380-384.

24. Shepard JB, DA Gliga, AP Morrow, S Hoffman and AA Capehart. 2008. Versican knock-down compromises chondrogenesis in the embryonic chick limb. Anat. Rec. 291:19-27.