Research Program
 

Research interests in my recent past have been focusing on the mechanisms of allergic responses as well as to identifying allergens from different sources which would help to lead to better diagnosis and treatment of this disease. My past research was focused on recombinant allergen using various biotechnological methods. 

I have very recently started collaborations with Dr. Matt Schrenk. In this new and exciting research will explore the diversity of the microbial world in its extreme environment.  We also will study the community of microbes forming biofilms and their influence on human health and environment.

BIOL 1100, Introductory Biology.

BIOL 2110, 2111. Microbiology for non-majors.

BIOL 4220, Microbes and Immunity.

BIOL 4170, Immunology.

Recent Publications

1. M. Schmidt and K.K. Sethi, "Production and Characterization of Monoclonal Antibodies Specific for Pathogenic Serogroups O:3, O:8 and O:9 of Yersinia enterocolitica", Zentralblatt f¸r Bakteriologie, Mikrobiologie und Hygiene A265, 113-123 (1987).
2. M. Schmidt, H. Ponstingl and F.A. Bautz, "A Monoclonal Antibody Directed Against the Head Region of Vimentin", Biochem. Biophys. Res. Commun. 146, 1366-1374 (1987).

3. U. Hilgenfeldt, G. Kienapfel, W. Kellerman, R. Schott and M. Schmidt, "Renin-Angiotensin System in Sepsis", Clin. and Exper. Hypertension - Theory and Practice A9 (8 & 9), 1453-1504 (1987).

4. D.R. Hoffman, A. Mason Smith, M. Schmidt, J.E. Moffitt and M. Guralnick, "Allergens in Hymenoptera Venom. XXII: Comparison of Venoms from Two Species of Imported Fire Ants, Solenopsis invicta and richteri ", J. Allergy Clin. Immunol. 85, 988-996 (1990).

5. D.R. Hoffman, R.S. Jacobson, M. Schmidt and A. Mason Smith, "Allergens in Hymenoptera Venoms XXIII. The Venom Content of Imported Fire Ant Whole Body Extracts", Annals of Allergy, 66, 29-31 (1991).

6. M. Schmidt, R.B. Walker, D.R. Hoffman, and T.J. McConnell, "Nucleotide Sequence of cDNA Encoding the Fire Ant Venom Protein Sol i II", FEBS Letters, 319, 138-140 (1993).

7. Y. Shibata, D.R. Bjorkman, M. Schmidt, Y. Oghiso, and A. Volkman, "Macrophage Colony Stimulating Factor-Induced Bone Marrow Macrophages do not Synthesize or Release Prostaglandin E2", Blood 83, 3316-3323 (1994).

8. M. Schmidt, S. Olsson, I. van der Ploeg, and M. van Hage-Hamsten, "cDNA Analysis of the Mite Allergen Lep d 1 Identifies Two Different Isoallergens and Variants", FEBS Letters 370, 11-14 (1995).

9. M. Schmidt, T.J. McConnell, and D. Hoffman, "Production of a Recombinant Imported Fire Ant Venom Allergen, Sol i 2, in Native and Immunoreactive Form", J. Allergy Clin. Immunol. 98, 82-88 (1996).

10. E. Johansson, M. Schmidt, S.G.O. Johansson, L. Machado, S. Olsson, and M. van Hage-Hamsten, "Allergenic Cross-reactivity Between Lepidoglyphus destructor and Blomia tropicalis ", Clin. and Exper. Allergy 27, 691-699 (1997).

11. M. Schmidt, A. Zargari, P. Holt, L. Lindbom, U. Hellman, P. Whitley, I. van der Ploeg, B. Harfast, and A. Scheynius, "The Complete cDNA Sequence and Expression of the First Major Allergenic Protein of Malassezia furfur, Mal f 1", Eur. J. Biochem. 246, 181-185 (1997).

12. T.L.J. Eriksson, E. Johansson, P. Whitley, M. Schmidt, E.Said, and M. van Hage-Hamsten, "Cloning and Charaterization of a Group II Allergen from the Dust Mite Tyrophagus putrescentiae", Eur. J. Biochem. 215, 443-447 (1998)

13. L.N. Soldatova, R.Crameri, M. Gmachl, D.M. Kemeny, M. Schmidt, M. Weber, and U. Muller, "A Comparative Study of the Recobinant Bee Venom Allergen, Hyaluronidase, Expressed in Bacterial and Insect Cells", J. Allergy Clin. Immunol. 101, 691-698 (1998).

14.  S. Olsson, M. van Hage-Hamsten, P. Whitley, E. Johansson, D.R. Hoffman, G. Gafvelin, and M. Schmidt, "Expression of Two Isoforms of Lep d 2, the Major Allergen of Lepidoglyphus destructor, in Both Prokaryotic and Eukaryotic Systems", Clin. and Exper. Allergy 28, 984-991 (1998).

15.  Elfman, Lotta H. M., P. Whitley, M. Schmidt, M. can Hage-Hamsten, "IgE Binding Capacity of Synthetic and Recombinant Peptides of the Major Storage Mite (Lepidoglyphus ddestructor) Allergen, Lep d 2",  Int Arch Allergy Immunol. 117: 167-173 (1998).

16.  A. Zargari, M. Schmidt, M. Lundberg, A. Scheynius, P. Whitley, " Immunologic Characterization of Natural and Recombinant Mal fl Yeast Allergen" , J Allergy and Clin. Immunol. 103, 877-884 (1999).

17.  M. Lindborg, C.G.M Magnusson, A. Zargari, M. Schmidt, A. Scheynius, R. Crameri, and P. Whitley, " Selective Cloning of Allergens from the Skin Colonizing Yeast Malassezia furfur by Phage Display Technology", J. Invest. Dermatology 113, 156-161 (1999).

18.  J.E.M. Bjorklund, M. Schmidt, and C.G.M. Magnusson,
" Characterization of Recombinant Human IgE-Fc Fragments Expressed in Baculovirus- Infected Insect Cells", Mol. Immunol. 37, 169-177 (2000).