Associate Professor, Department of Chemistry
Adjunct Associate Professor, Department of Pharmacology and Toxicology
Office: Science and Technology Building 591
Phone: (252) 328-9766
Postdoctoral Fellow, Rowland Institute at Harvard (2002-2004)
Ph.D., Chemistry, University of North Carolina at Chapel Hill (2001)
B.S., Chemistry, Truman State University (1996)
Analytical chemistry research in the Danell Lab is focused on fundamental studies and applications of mass spectrometry technology. Mass spectrometry analysis occurs in a unique environment because there is no water or other solvent surrounding the molecules inside a mass spectrometer. We are particularly interested in learning more about gas phase structure to further the application of mass spectrometry to problems of biological significance. Project areas include:
Robb, A. J.*; Vinogradov, S. M.**; Danell, A. S.; Anderson, E.; Blackledge,
M. S.; Melander, C.; Hvastkovs, E. G. "Electrochemical Detection of
Small Molecule Induced Pseudomonas aeruginosa Biofilm Dispersion." Electrochim. Acta, 2018, 268, 276-282.
Soliman, E., Henderson, K. L.**, Danell, A. S., and Van Dross, R. "Arachidonoyl-ethanolamide Activates Endoplasmic Reticulum Stress-Apoptosis in Tumorigenic Keratinocytes: Role of Cyclooxygenase-2 and Novel J-series Prostamides." Mol. Carcinog. 2016, 55, 117-130. DOI:10.1002/mc.22257
Ellison, M. L., Farrow III, J. M., Parrish, W. A.**, Danell, A. S., and Pesci, E. C. "The Transcriptional Regulator Np20 is the Zinc Uptake Regulator in Pseudomonas aeruginosa." PLoS One. 2013, 8, e75389.
Satterwhite, J. E.**; Trumbo, C. M.**; Danell, A. S.; Hvastkovs, E. G. "Electrochemical Study on the Effects of Epigenetic Cytosine Methylation on Anti-Benzo[a]pyrene Diol Epoxide Damage at TP53 Oligomers." Anal. Chem. 2013, 83, 1183-1191.
Satterwhite, J. E.**; Pugh, A. M.*; Danell, A. S.; Hvastkovs, E. G. "Electrochemical Detection of anti-Benzo[a]pyrene Diol Epoxide DNA damage on TP53 Codon 273 Oligomers", Anal. Chem. 2011, 83, 3327-3335.
Myer, M. J.**; Danell, R. M.; Danell, A. S. "A Simple Dual Polarity Dual nanoElectrospray Ionization Source for Ion/Ion Reactions", Rev. Sci. Instrum. 2010, 81, 066103.
Mattapalli, H.**; Monteith, W. B.*; Burns, C. S.; Danell, A. S. "Zinc Deposition During ESI-MS Analysis of Peptide-Zinc Complexes", J. Am. Soc. Mass Spectrom. 2009, 20, 2199-2205.
Romack, T. J.; Danell, A. S.; Cottone, T. M.*; Dutta, S. K. "Electrospray Ionization Time of Flight Mass Spectrometry Characterization of Perfluoroalkyl Acrylic Oligomers", Rapid Commun. Mass Spectrom. 2008, 22, 930-934.
Unnithan, A. G.*; Myer, M. J.**; Veale, C. J.*; Danell, A. S. "MS/MS of Protonated Polyproline Peptides: The Influence of N-terminal Protonation on Dissociation", J. Am. Soc. Mass Spectrom. 2007, 18, 2198-2203.
Wilson, C. L.**; Monteith, W. B.*; Danell, A. S.; Burns, C. S. "Purification and Characterization of the Central Segment of Prothymosin-a: Methodology for Handling Highly Acidic Peptides", J. Peptide Sci. 2006, 12, 721-725.
* ECU undergraduate student ** ECU graduate student
J-series prostaglandin-ethanolamides as novel therapeutics. US Patent 9,328,060, May 3, 2016.