Contact Information

Office: SZ 552
Phone: (252) 328-9790

Colin S. Burns
Publications and Patents

East Carolina University

"Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, D12,14-Prostamide J2, as a Selective Anti-Tumor Therapeutic" Daniel A. Ladin, Eman Soliman, Rene Escobedo, Timothy L. Fitzgerald, Li V. Yang, Colin Burns, and Rukiyah Van Dross Molecular Cancer Therapeutics 2017 DOI: 10.1158.1535-7163.MCT-16-0484.

"J-Series Prostaglandin-Ethanolamides as Novel Therapeutics" Rukiyah T. Van Dross, Daniel A. Ladin, Colin S. Burns, Allison Stokes Danell US Patent 9,328,060, May 3, 2016

"Calorimetric Investigation of Copper Binding in the N-Terminal Region of the Prion Protein at Low Copper Loading: Evidence for an Entropically Favorable First Binding Event" Devi Praneetha Gogineni, Anne M. Spuches, and Colin S. Burns* Inorganic Chemistry 2015, 54, 441-447.

"Field- and Temperature-Dependent 13C NMR Studies of the EDTA-Zn2+ Complex: Insight into Structure and Dynamics via Relaxation Measurements" Sriramya Garapati, Colin S. Burns*, and Art A. Rodriguez* Journal of Physical Chemistry B 2014, 118, 12960-12964.

"The 4-pyridylmethyl ester as a protecting group for glutamic and aspartic acids: 'flipping' peptide charge states for characterization by positive ion mode ESI-MS" Sriramya Garapati and Colin S. Burns* Journal of Peptide Science 2014, 20, 191-195.

"Peculiarities of Copper Binding to Alpha-Synuclein" Atta Ahmad*, Colin S. Burns*, Anthony L. Fink, and Vladimir N. Uversky* Journal of Biomolecular Structure and Dynamics 2012, 29, 825-842.

"Prothymosin-alpha Inhibits HIV-1 via Toll-like Receptor 4-Mediated Type I Interferon Induction" Arevik Mosoian, Avelino Teixeira, Colin S. Burns, Leif E. Sander, G. Luca Gusella, Cijing He, J. Magarian Blander, Paul Klotman and Mary Klotman* Proceedings of the National Academy of Sciences 2010, 107, 10178-10183.

"Zinc Deposition During ESI-MS Analysis of Peptide-Zinc Complexes" Haritha Mattapalli, William B. Monteith, Colin S. Burns and Allison Danell* Journal of the American Society for Mass Spectrometry 2009, 20, 2199-2205.

"The Manganese Transporter MntH is a Critical Determinant for Brucella Abortus 2308 in Experimentally Infected Mice" Eric S. Anderson, James T. Paulley, Jennifer M. Gaines, Michelle W. Valderas, Daniel W. Martin, Evan Menscher, Timothy D. Brown, Colin S. Burns and Martin Roop II* Infection and Immunity 2009, 77, 3466-3474.

"Identification of the Cu(II) Coordinating Residues in the Prion Protein by Metal-Catalyzed Oxidation Mass Spectrometry: Evidence for Multiple Isomers at Low Cu(II) Loadings" Rapole Srikanth, Jonathan Wilson, Colin S. Burns* and Richard W. Vachet* Biochemistry 2008, 47, 9258-9268.

"Characterization of the Cu2+ Binding Modes in the Prion Protein by Visible CD and Multivariate Curve Resolution" J. Bryant Pollock, Patrick J. Cutler, John M. Kenney, Paul J. Gemperline and Colin S. Burns* Analytical Biochemistry 2008, 377, 223-233.

"Influence of Prothymosin-a on HIV-1 Target Cells" Arevik Mosoian, Avelino Teixeira, Colin S. Burns, Gregory Khitrov, Weijia Zhang, Luca Gusella, Paul Klotman and Mary Klotman* Annals of the New York Academy of Sciences 2007, 1112, 269 285.

"Copper and Zinc Promote Interactions between Membrane Anchored Peptides of the Metal Binding Domain of the Prion Protein" Angela G. Kenward, Libero J. Bartolotti and Colin S. Burns* Biochemistry 2007, 46, 4261-4271.

"Purification and characterization of the central segment of prothymosin-a: Methodology for handling highly acidic peptides" Christopher L. Wilson, William B. Monteith, Allison S. Danell and Colin S. Burns* Journal of Peptide Science 2006, 12, 721- 725.

University of California at Santa Cruz

"Molecular Features of the Copper Coordination Sites in the Full Length, Recombinant Prion Protein" Colin S. Burns, Eliah Aronoff Spencer, Giuseppe Legname, Stanley B.Prusiner, William E. Antholine, Gary J. Gerfen, Jack Peisach, and Glenn L. Millhauser* Biochemistry 2003, 42, 6794-6803.

“Optical and Surface Structural Properties of Mn2+ Doped ZnSe Nanoparticles” Thaddeus J. Norman Jr., Donny Magana, Thea Wilson, Colin S. Burns, and Jin Z. Zhang* Journal of Physical Chemistry B 2003, 107, 6309-6317.

"Molecular Features of the Copper Binding Sites in the Octarepeat Domain of the Prion Protein" Colin S. Burns, Eliah Aronoff-Spencer, Christine M. Dunham*, Paula Lario, Nikolai I. Avdievich, William E. Antholine, Marilyn M. Olmstead, Alice Vrielink, Gary J. Gerfen, Jack Peisach, William G. Scott, and Glenn L. Millhauser* Biochemistry 2002, 41, 3991-4001.

"Identification of the Cu2+ Binding Sites in the N-Terminal Domain of the Prion Protein by EPR and CD Spectroscopy" Eliah Aronoff Spencer, Colin S. Burns, Nikolai I. Avdievich, Gary J. Gerfen, Jack Peisach, William E. Antholine, Haydn L. Ball, Fred E. Cohen, Stanley B. Prusiner, and Glenn L. Millhauser* Biochemistry 2000, 39, 13760-13771.

University of North Carolina at Chapel Hill

"Mechanism for Formation of the Lightstruck Flavor of Beer” Colin S. Burns, Arne Heyrick, Denis De Keukeleire, and Malcolm D. E. Forbes* Chemistry: A European Journal 2001, 7, 4553-4561.

"Neutral Peptide Biradicals Formed by Dissociative Electron Transfer" Colin S. Burns, Lakecia Rochelle, and Malcolm D. E. Forbes* Organic Letters 2001, 3, 2197-2200.