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Research Interest:

The study of biological processes on a molecular level.

Dr. Martin Bier

Dr Martin Bier
  • Associate Professor
  • PhD., Clarkson University, 1990
  • Office Location: Austin 328
  • Office Hours: Monday, Wednesday, Friday 11:00am -1:00pm
  • Telephone: (252) 328-6428
  • Email: bierm@ecu.edu
  • Homepage: http://personal.ecu.edu/bierm/

Publications:

Bier, M. & Gallaher, J. (2011), ION TRAFFIC THROUGH A CELL MEMBRANE -- AND HOW ITS 1/f NOISE CONNECTS TO GAMBLER'S RUIN, CATALAN NUMBERS AND ZIPF'S LAW.  Fluctuation and Noise Letters, 10 (4), 419-430.  

Kassahun, B. T., Murashov, A. K., & Bier, M. (2010). A Thermodynamic Mechanism behind an Action Potential and behind Anesthesia.  Biophysical Reviews and Letters, 5 (1), 35-41.  

Gallaher, J., Siegenbeek van Heukelom, J., & Bier, M. (2010). First Order Phase Transition and Hysteresis in a Cell's Maintenance of the Membrane Potential An Essential Role for the Inward Potassium Rectifiers.  BioSystems, 101, 149-155.  

Bier, M. & Cao, F. J. (2011).  How occasional back stepping can speed up a processive motor protein.  BioSystems, 103 (3), 355-359.  

Gallaher, J., Wodzinska, K., Heimburg, T., & Bier, M. (2010). Ion-channel-like Behavior in Lipid Bilayer Membranes at the Melting Transition.  Physical review E, 81, 061925.  

Bier, M. (2010). Quantum Consciousness and Other Spooky Myths.  Skeptic Magazine, 16 (1), 40-43.  

M. Bier. The Energetics, Chemistry, and Mechanics of a Processive Motor Protein BioSystems93, 23-28, (2008).

M. Bier.  Accounting for the Energies and Entropies of KinesinÕs Catalytic Cycle European Physical Journal B65, 415-418, (2008).

M. Bier. The Stepping Motor Protein as a Feedback Control RatchetBioSystems88, 301-307, (2007).

M. Bier, O.W. Day, and D.W. Pravica, Murmurs and Noise Caused by Arterial Narrowing - Theory and Clinical Practice Fluctuation and Noise Letters6 (4), 415-425, 2006.

M. Bier, How to Evaluate the Electric Noise in a Cell Membrane Acta Physical Polonica B37 (5), 1409-1424, 2006.

D.W. Pravica, M. Bier, R.S. Brock, and O.W. Day, Stable Stationary Vortices and Traveling Oscillatory Vortices in a Stenotic Fluid-flow Channel Physical Review E72, 067303, 2005.

M. BierGauging the Strength of Power Frequency Fields against Membrane Electric Noise Bioelectromagnetics26, 595-609, 2005.

M. Bier, W. Chen, E. Bodnar, and R.C. Lee, Biophysical Injury Mechanisms Associated with Lightning Injury Neurorehabilitation20(1), 53-62, 2005.

M. BierCritical Exponents near a Bifurcation Point in Noise Induced Escape over a Fluctuating Barrier Physical Review E71(1), 011108, 2005.

M. BierModeling Processive Motor Proteins - Moving on Two Legs in the Microscopic Realm Contemporary Physics46 (no 1), 41-51, 2005.

M. Bier, T.R. Gowrishankar, W. Chen, and R.C. Lee, The Electroporation of a Lipid Bilayer as a Chemical Reaction Bioelectromagnetics25 (no 8), 634-637, 2004.

H. van Mil, J. Siegenbeek van Heukelom, and M. Bier, A Bistable Membrane Potential at Low Extracellular Potassium Concentration Biophysical Chemistry106, 15-21, 2003.

M. BierProcessive Motor Protein as an Overdamped Brownian Stepper Physical Review Letters 91 (14), 148104, 2003.

M. Bier, T.R. Gowrishankar, W. Chen, R.D. Astumian, and R.C. Lee, Resealing Dynamics of a Cell Membrane after Electroporation Physical Review E66, 062905, 2002.

M. BierMotor Proteins - Mechanochemical Energy Transduction on the Microscopic Scale Acta Physica Polonica B32 (2), 287-294, 2001.

M. Bier, M. Kostur, I. Derenyi, and R.D. Astumian, Nonlinearly Coupled Flows Physical Review E61 (6), 7184 - 7187, 2000.

M. Bier, B.M. Bakker and H.V. Westerhoff, How Yeast Cells Synchronize their Glycolytic Oscillations - A Perturbation Analytic Treatment Biophysical Journal78, 1166-1175, 2000.

I. Derenyi, M. Bier and R.D. Astumian, The Generalized Efficiency and its Application to Microscopic Engines Physical Review Letters83 (5), 903 - 906, 1999.

M. Bier, I. Derenyi, M. Kostur and R.D. Astumian,The Intrawell Relaxation of Overdamped Brownian Particles Physical Review E59 (6), 6422 - 6432, 1999.

M. Bier, S. M. Hammer, D.J. Canaday, and R.C. Lee,Kinetics of Sealing for Transient Electropores in Isolated Skeletal Muscle Bioelectromagnetics20 (no.3), 194 - 201, 1999.

M. Bier and R.D. Astumian,What is Adiabaticity? - Suggestions from a Fluctuating Linear Potential Physics Letters A247 (no.6), 385 - 390, 1998.

M. BierBrownian Ratchets in Physics and Biology Contemporary Physics38 (no.6), 371- 379, 1997.

M. Bier, B. Teusink, B.N. Kholodenko and H.V. Westerhoff, Control Analysis of Glycolytic Oscillations Biophysical Chemistry62, 15-24, 1996.

G.S. Abramov, M. Bier, M. Capelli-Schellpfeffer, and R.C. Lee, Alteration in Sensory Nerve Function Following Electrical Shock Burns, 22 (no. 8), 602-606, 1996.

M. Bier and R. D. Astumian, Biasing Brownian Motion in Different Directions in a 3 State Fluctuating Potential and an Application for the Separation of Small Particles Physical Review Letters76, 4277-4280, 1996.

M. Bier, K.S. Kits, and J.G.G. Borst, The Relation between Risetimes and Amplitudes of GABA-ergic Postsynaptic CurrentsJournal of Neurophysiology, 75, (no. 3), 1008-1012, 1996.

R.D. Astumian and M. Bier Mechanochemical Coupling of of the Motion of Molecular Motors to ATP Hydrolysis Biophysical Journal70, 637-653, 1996.

M. Bier and R.D. Astumian, Biased Brownian Motion as the Operating Principle for Microscopic Engines Bioelectrochemistry & Bioenergetics39, 67-75, 1996.

M. BierReversals of Noise Induced FlowPhysics Letters A211 (no. 1), 12-18, 1996.

P.R. Jensen, A.A. Van der Gugten, M. Bier, W.C. Van Heeswijk, J. Rohwer, D. Molenaar, D. Van Workum, P. Richard, B. Teusink, B.M. Bakker, B.N. Kholodenko, and H.V. Westerhoff, Hierarchies in Control Journal of Biological Systems3 (no. 1), 187-196, 1995.

J.G.G. Borst, K.S. Kits, and M. BierVariance analysis of GABA-ergic in IPSCs of Melanotropes from Xenopus Laevis Biophysical Journal67, 183-189, 1994.

R.D. Astumian and M. BierFluctuation Driven Ratchets - Molecular MotorsPhysical Review Letters72 (no 11), 1766-1769, 1994.

Other Publications:

M. BierThe Noisy Steps of a Motor Protein. in UPoN 2002: 3rd International Conference on Unsolved Problems of Noise and Fluctuations in Physics, Biology, and High TechnologyEdited by Sergey M. Bezrukov, "AIP Conference Proceedings 665" Washington, DC 2002. p290-297.

M. Bier and M. Kostur, Nonlinearly Coupled Chemical Reactions in Stochastic Processes in Physics, Chemistry and Biology Eds. J. A. Freund and T. Poeschel , Springer Series "Lecture Notes on Physics 557" Springer-Verlag, Berlin 2000. p206-211.

M. BierA Motor Protein Model and how it Relates to Stochastic Resonance, Feynman's Ratchet and Maxwell's Demon in Lectures on Stochastic Dynamics Eds. L. Schimansky-Geier and T. Poeschel, Springer Series "Lecture Notes on Physics 484" Springer-Verlag, 1997. p29-35.

M. Bier, J.G.G. Borst and K.S. Kits,On Inferring the Kinetic Scheme of an Ion Channel from Postsynaptic Currentsin Biomedical Physics Horizons Edited by D.N. Ghista, 1996. p115 - 124.

H.V. Westerhoff, M. Bier, D. Molenaar, E.C. Spoelstra, J. Lankelma, A.P.M. Jongsma, P.R. Jensen, P. Richard and B.N. Kholodenko, Control of Dynamics and Steady State; Theory and Applications to Multidrug Resistancein Biomedical Physics Horizons Edited by D.N. Ghista, 1996.p25-31.