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Research Interest:

The study of biological processes on a molecular level.

Dr. Martin Bier

Bier
  • Associate Professor
  • PhD., Clarkson University, 1990
  • Office Location: Austin 328
  • Office Hours: Monday, Wednesday, Friday 11:00am -1:00pm
  • Telephone: (252) 328-6428
  • Email: bierm@ecu.edu
  • Homepage: http://personal.ecu.edu/bierm/

Publications:

Bier, M. & Gallaher, J. (2011).  ION TRAFFIC THROUGH A CELL MEMBRANE -- AND HOW ITS 1/f NOISE CONNECTS TO GAMBLER'S RUIN, CATALAN NUMBERS AND ZIPF'S LAW.  Fluctuation and Noise Letters, 10 (4), 419-430.  

Kassahun, B. T., Murashov, A. K., & Bier, M. (2010).  A Thermodynamic Mechanism behind an Action Potential and behind Anesthesia.  Biophysical Reviews and Letters, 5 (1), 35-41.  

Gallaher, J., Siegenbeek van Heukelom, J., & Bier, M. (2010).  First Order Phase Transition and Hysteresis in a Cell's Maintenance of the Membrane Potential An Essential Role for the Inward Potassium Rectifiers.  BioSystems, 101, 149-155.  

Bier, M. & Cao, F. J. (2011).  How occasional backstepping can speed up a processive motor protein.  BioSystems, 103 (3), 355-359.  

Gallaher, J., Wodzinska, K., Heimburg, T., & Bier, M. (2010).  Ion-channel-like Behavior in Lipid Bilayer Membranes at the Melting Transition.  Physical review E, 81, 061925.  

Bier, M. (2010).  Quantum Consciousness and Other Spooky Myths.  Skeptic Magazine, 16 (1), 40-43.  

M. Bier,The Energetics, Chemistry, and Mechanics of a Processive Motor ProteinBioSystems93, 23-28, (2008).

M. Bier,Accounting for the Energies and Entropies of KinesinÕs Catalytic CycleEuropean Physical Journal B65, 415-418, (2008).

M. Bier,The Stepping Motor Protein as a Feedback Control RatchetBioSystems88, 301-307, (2007).

M. Bier, O.W. Day, and D.W. Pravica,Murmurs and Noise Caused by Arterial Narrowing - Theory and Clinical PracticeFluctuation and Noise Letters6 (4), 415-425, 2006.

M. Bier,How to Evaluate the Electric Noise in a Cell MembraneActa Physica Polonica B37 (5), 1409-1424, 2006.

D.W. Pravica, M. Bier, R.S. Brock, and O.W. Day,Stable Stationary Vortices and Traveling Oscillatory Vortices in a Stenotic Fluid-flow ChannelPhysical Review E72, 067303, 2005.

M. Bier,Gauging the Strength of Power Frequency Fields against Membrane Electric NoiseBioelectromagnetics26, 595-609, 2005.

M. Bier, W. Chen, E. Bodnar, and R.C. Lee,Biophysical Injury Mechanisms Associated with Lightning InjuryNeurorehabilitation20(1), 53-62, 2005.

M. Bier,Critical Exponents near a Bifurcation Point in Noise Induced Escape over a Fluctuating BarrierPhysical Review E71(1), 011108, 2005.

M. Bier,Modeling Processive Motor Proteins - Moving on Two Legs in the Microscopic RealmContemporary Physics46 (no 1), 41-51, 2005.

M. Bier, T.R. Gowrishankar, W. Chen, and R.C. Lee,The Electroporation of a Lipid Bilayer as a Chemical ReactionBioelectromagnetics25 (no 8), 634-637, 2004.

H. van Mil, J. Siegenbeek van Heukelom, and M. Bier,A Bistable Membrane Potential at Low Extracellular Potassium ConcentrationBiophysical Chemistry106, 15-21, 2003.

M. Bier,Processive Motor Protein as an Overdamped Brownian StepperPhysical Review Letters91 (14), 148104, 2003.

M. Bier, T.R. Gowrishankar, W. Chen, R.D. Astumian, and R.C. Lee,Resealing Dynamics of a Cell Membrane after ElectroporationPhysical Review E66, 062905, 2002.

M. Bier,Motor Proteins - Mechanochemical Energy Transduction on the Microscopic ScaleActa Physica Polonica B32 (2), 287-294, 2001.

M. Bier, M. Kostur, I. Derenyi, and R.D. Astumian,Nonlinearly Coupled FlowsPhysical Review E61 (6), 7184 - 7187, 2000.

M. Bier, B.M. Bakker and H.V. Westerhoff,How Yeast Cells Synchronize their Glycolytic Oscillations - A Perturbation Analytic TreatmentBiophysical Journal78, 1166-1175, 2000.

I. Derenyi, M. Bier and R.D. Astumian,The Generalized Efficiency and its Application to Microscopic EnginesPhysical Review Letters83 (5), 903 - 906, 1999.

M. Bier, I. Derenyi, M. Kostur and R.D. Astumian,The Intrawell Relaxation of Overdamped Brownian ParticlesPhysical Review E59 (6), 6422 - 6432, 1999.

M. Bier, S. M. Hammer, D.J. Canaday, and R.C. Lee,Kinetics of Sealing for Transient Electropores in Isolated Skeletal MuscleBioelectromagnetics20 (no.3), 194 - 201, 1999.

M. Bier and R.D. Astumian,What is Adiabaticity? - Suggestions from a Fluctuating Linear PotentialPhysics Letters A247 (no.6), 385 - 390, 1998.

M. Bier,Brownian Ratchets in Physics and BiologyContemporary Physics38 (no.6), 371- 379, 1997.

M. Bier, B. Teusink, B.N. Kholodenko and H.V. Westerhoff,Control Analysis of Glycolytic OscillationsBiophysical Chemistry62, 15-24, 1996.

G.S. Abramov, M. Bier, M. Capelli-Schellpfeffer, and R.C. Lee,Alteration in Sensory Nerve Function Following Electrical ShockBurns, 22 (no. 8), 602-606, 1996.

M. Bier and R. D. Astumian,Biasing Brownian Motion in Different Directions in a 3 State Fluctuating Potential and an Application for the Separation of Small ParticlesPhysical Review Letters76, 4277-4280, 1996.

M. Bier, K.S. Kits, and J.G.G. Borst,The Relation between Risetimes and Amplitudes of GABA-ergic Postsynaptic CurrentsJournal of Neurophysiology, 75, (no. 3), 1008-1012, 1996.

R.D. Astumian and M. Bier,Mechanochemical Coupling of of the Motion of Molecular Motors to ATP HydrolysisBiophysical Journal70, 637-653, 1996.

M. Bier and R.D. Astumian,Biased Brownian Motion as the Operating Principle for Microscopic EnginesBioelectrochemistry & Bioenergetics39, 67-75, 1996.

M. Bier,Reversals of Noise Induced FlowPhysics Letters A211 (no. 1), 12-18, 1996.

P.R. Jensen, A.A. Van der Gugten, M. Bier, W.C. Van Heeswijk, J. Rohwer, D. Molenaar, D. Van Workum, P. Richard, B. Teusink, B.M. Bakker, B.N. Kholodenko, and H.V. Westerhoff,Hierarchies in ControlJournal of Biological Systems3 (no. 1), 187-196, 1995.

J.G.G. Borst, K.S. Kits, and M. Bier,Variance analysis of GABA-ergic in IPSCs of Melanotropes from Xenopus LaevisBiophysical Journal67, 183-189, 1994.

R.D. Astumian and M. Bier,Fluctuation Driven Ratchets - Molecular MotorsPhysical Review Letters72 (no 11), 1766-1769, 1994.

Other Publications:

M. Bier,The Noisy Steps of a Motor Protein. inUPoN 2002: 3rd International Conference on Unsolved Problems of Noise and Fluctuations in Physics, Biology, and High TechnologyEdited by Sergey M. Bezrukov, "AIP Conference Proceedings 665" Washington, DC 2002. p290-297.

M. Bier and M. Kostur,Nonlinearly Coupled Chemical ReactionsinStochastic Processes in Physics, Chemistry and BiologyEds. J. A. Freund and T. Poeschel , Springer Series "Lecture Notes on Physics 557" Springer-Verlag, Berlin 2000. p206-211.

M. Bier,A Motor Protein Model and how it Relates to Stochastic Resonance, Feynman's Ratchet and Maxwell's DemoninLectures on Stochastic DynamicsEds. L. Schimansky-Geier and T. Poeschel, Springer Series "Lecture Notes on Physics 484" Springer-Verlag, 1997. p29-35.

M. Bier, J.G.G. Borst and K.S. Kits,On Inferring the Kinetic Scheme of an Ion Channel from Postsynaptic CurrentsinBiomedical Physics HorizonsEdited by D.N. Ghista, 1996. p115 - 124.

H.V. Westerhoff, M. Bier, D. Molenaar, E.C. Spoelstra, J. Lankelma, A.P.M. Jongsma, P.R. Jensen, P. Richard and B.N. Kholodenko,Control of Dynamics and Steady State; Theory and Applications to Multidrug ResistanceinBiomedical Physics HorizonsEdited by D.N. Ghista, 1996.p25-31.