David P. Cistola, M.D., Ph.D.
Associate Dean for Research
Professor of Clinical Laboratory Science
College of Allied Health Sciences
Professor of Biochemistry & Molecular Biology
Brody School of Medicine
Education and Training:
B.S., Biochemistry, State University of New York, Binghamton, 1978
M.D., Ph.D., Medicine, Biochemistry & Biophysics,
Boston University School of Medicine, 1985
NIH National Research Service Award Fellow, 1985-86
Juvenile Diabetes Foundation Fellow, 1987-88
Prior Faculty appointment:
Washington University School of Medicine, St. Louis, 1989-2007
Current Roles and Responsibilities at ECU:
Associate Dean for Research: provide administrative leadership to strengthen the research culture and external grant support at the college and university level; oversee the CAHS Grants Office
Lead Principal Investigator of Operation Re-entry North Carolina, a university-wide research initiative in support of military personnel and their families; supported by a 5-year cooperative agreement with the U.S. Army Medical Research and Material Command, 2.1M in year one
Principal Investigator of the NMR Diagnostics Research Laboratory, which conducts translational research in diabetes, cardiovascular disease & military blast injury
Federal Advisory and Review Panels:
Chair, NIH F04B Study Section,ZRG1 F04BB, Fellowships in Biophysical and Biochemical Sciences, Interdisciplinary Molecular Sciences and Training IRG, May 2010 – April 2011
Rehabilitation Peer Review Panel, Defense Medical Research and Development Program, Applied Research and Advanced Technology Development Awards, DoD, 2009
NIH F04B Fellowship Review Panel, 2005, 2009
Military Relevance Review Panel, DoD Congressionally Directed Medical Research Program (CDMRP), Deployment Related Medical Research Program, US Army, 2008
NIH Special Emphasis Panel, ZRG1 BCMB-L3 (high-end NMR instrumentation), 2006
NIH Special Emphasis Review Panel, ZRG1 BPC-L 30 (NMR S10 instrumentation), 2004
NIH Special Emphasis Review Panel, ZRG1 SSS-A (NMR instrumentation), 2002
NIH Shared Instrumentation Grants Review Panel, 2001
NIH Biophysical Chemistry Study Section, BBCB, 1996
NIH Special Study Section 7, 1995
University Appointments and Committees –ECU:
University Committee on Intellectual Property and Patents
Associate Deans Research Council
University Biological Safety Committee (2007-2008)
Diabetes and Obesity Institute Steering Committee
Graduate School Administrative Board (ex officio)
Graduate Enrollment and F&A Task Forces
Innovate to Collaborate to Accelerate Initiative
Honors, Awards, Fellowships:
Dean's Award for Outstanding Performance in Service, CAHS, 2010
ECU Chancellor's Leadership Fellow, 2009
Johnson & Johnson/Merck Research Scholar, American Digestive Health Foundation, 1992-1995
Faculty Award, Markey Center for Research in the Molecular Biology of Human Disease at Washington University, 1991-1993
Andrew Costello Fellowship, Juvenile Diabetes Foundation International, 1987-1988
National Research Service Award, NIH Postdoctoral Fellowship, 1985-1986
Student Award, American Federation for Clinical Research, 1983
Honored Student Award, American Oil Chemist's Society, 1983
National Research Service Award, NIH Predoctoral Fellowship, 1980-1983
Aswad Family Award for an Outstanding Student Going on to Medical School, SUNY Binghamton Foundation, 1978
Outstanding Academic Performance Award, Harpur College, SUNY Binghamton, 1978
Beck, M.R., DeKoster, G.T., Cistola, D.P. & Goldman, W.E. (2009) NMR structure of a fungal virulence factor reveals structural homology with mammalian saposin B. Molecular Microbiology 72: 344-353.
Toke, O., Monsey, J.D., DeKoster, G.T., Tochtrop, G.P., Tang, C. & Cistola, D.P. (2006) Determinants of cooperatively and site-selectivity in human ileal bile acid binding protein. Biochemistry 45:727-37.
Tochtrop, G.P., DeKoster, G.T., Covey, D.F. & Cistola, D.P. (2004) A single hydroxyl group governs ligand site selectivity in human ileal bile acid binding protein. J. Am. Chem. Soc.126:11024-11029.
Ogbay, B., Dekoster, G.T. & Cistola, D.P. (2004) The NMR structure of a stable and compact all-beta-sheet variant of intestinal fatty acid-binding protein. Protein Science 13:1227-1237.
Tochtrop, G.P., Richter, K, Tang, C., Toner, J.J., Covey, D.F. & Cistola, D. P. (2002) Energetics by NMR: Site-specific binding in a positively cooperative system. Proc. Natl. Acad. Sci. USA. 99:1847-1852.
Hodsdon, M.E., & Cistola, D.P. (1997) Discrete backbone disorder in the NMR structure of apo intestinal fatty acid-binding protein: Implications for the mechanism of ligand entry. Biochemistry 36, 1450-1460.
Hodsdon, M.E., Ponder, J.W., & Cistola, D.P. (1996) The NMR solution structure of intestinal fatty acid-binding protein complexed with palmitate: Application of a novel distance geometry algorithm. J. Mol. Biol. 264, 585-602.
MS 668 Allied Health Deans Office, Health Sciences Building
600 Moye Boulevard
Greenville, NC 27834