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College of Allied Health Sciences
Associate Dean for Research



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David P. Cistola, M.D., Ph.D.
Associate Dean for Research
Professor of Clinical Laboratory Science
College of Allied Health Sciences

Professor of Biochemistry & Molecular Biology
Brody School of Medicine

Education and Training:

 
B.S., Biochemistry, State University of New York, Binghamton, 1978


M.D., Ph.D., Medicine, Biochemistry & Biophysics,
Boston University School of Medicine, 1985


NIH National Research Service Award Fellow, 1985-86


Juvenile Diabetes Foundation Fellow, 1987-88 

 

Prior Faculty appointment: 


Washington University School of Medicine, St. Louis, 1989-2007

Current Roles and Responsibilities at ECU:

Associate Dean for Research:  provide administrative leadership to strengthen the research culture and external grant support at the college and university level; oversee the CAHS Grants Office  

Lead Principal Investigator of Operation Re-entry North Carolina, a university-wide research initiative in support of military personnel and their families; supported by a 5-year cooperative agreement with the U.S. Army Medical Research and Material Command, 2.1M in year one

Principal Investigator of the NMR Diagnostics Research Laboratory, which conducts translational research in diabetes, cardiovascular disease & military blast injury

 

Federal Advisory and Review Panels:

  
Chair,
NIH F04B Study Section,ZRG1 F04BB, Fellowships in Biophysical and Biochemical Sciences, Interdisciplinary Molecular Sciences and Training IRG, May 2010 – April 2011

Rehabilitation Peer Review Panel, Defense Medical Research and Development Program, Applied Research and Advanced Technology Development Awards, DoD, 2009

NIH F04B Fellowship Review Panel, 2005, 2009
 
Military Relevance Review Panel, DoD Congressionally Directed Medical Research Program (CDMRP), Deployment Related Medical Research Program, US Army, 2008

NIH Special Emphasis Panel, ZRG1 BCMB-L3 (high-end NMR instrumentation), 2006

NIH Special Emphasis Review Panel, ZRG1 BPC-L 30 (NMR S10 instrumentation), 2004

NIH Special Emphasis Review Panel, ZRG1 SSS-A (NMR instrumentation), 2002

NIH Shared Instrumentation Grants Review Panel, 2001

NIH Biophysical Chemistry Study Section, BBCB, 1996

NIH Special Study Section 7, 1995

  

University Appointments and Committees ECU:

 
University Committee on Intellectual Property and Patents

Associate Deans Research Council

University Biological Safety Committee (2007-2008)

Diabetes and Obesity Institute Steering Committee

Graduate School Administrative Board (ex officio)

Graduate Enrollment and F&A Task Forces

Innovate to Collaborate to Accelerate Initiative

  

Honors, Awards, Fellowships:

  
Dean's Award for Outstanding Performance in Service, CAHS, 2010

ECU Chancellor's Leadership Fellow, 2009

Johnson & Johnson/Merck Research Scholar, American Digestive Health Foundation, 1992-1995

Faculty Award, Markey Center for Research in the Molecular Biology of Human Disease at Washington University, 1991-1993

Andrew Costello Fellowship, Juvenile Diabetes Foundation International, 1987-1988

National Research Service Award, NIH Postdoctoral Fellowship, 1985-1986

Student Award, American Federation for Clinical Research, 1983

Honored Student Award, American Oil Chemist's Society, 1983

National Research Service Award, NIH Predoctoral Fellowship, 1980-1983 
           
Aswad Family Award for an Outstanding Student Going on to Medical School, SUNY Binghamton Foundation, 1978 
                                    
Outstanding Academic Performance Award, Harpur College, SUNY Binghamton, 1978

Selected Publications:  

Beck, M.R., DeKoster, G.T., Cistola, D.P. & Goldman, W.E. (2009) NMR structure of a fungal virulence factor reveals structural homology with mammalian saposin B.  Molecular Microbiology 72: 344-353.  

Toke, O., Monsey, J.D., DeKoster, G.T., Tochtrop, G.P., Tang, C. & Cistola, D.P. (2006) Determinants of cooperatively and site-selectivity in human ileal bile acid binding protein.  Biochemistry 45:727-37.  

Tochtrop, G.P., DeKoster, G.T., Covey, D.F. & Cistola, D.P. (2004) A single hydroxyl group governs ligand site selectivity in human ileal bile acid binding protein. J. Am. Chem. Soc.126:11024-11029.

Ogbay, B., Dekoster, G.T. & Cistola, D.P. (2004) The NMR structure of a stable and compact all-beta-sheet variant of intestinal fatty acid-binding protein.  Protein Science 13:1227-1237.

Tochtrop, G.P., Richter, K, Tang, C., Toner, J.J., Covey, D.F. & Cistola, D. P. (2002) Energetics by NMR: Site-specific binding in a positively cooperative system. Proc. Natl. Acad. Sci. USA. 99:1847-1852.  

Hodsdon, M.E., & Cistola, D.P. (1997) Discrete backbone disorder in the NMR structure of apo intestinal fatty acid-binding protein:  Implications for the mechanism of ligand entry.  Biochemistry 36, 1450-1460.  

Hodsdon, M.E., Ponder, J.W., & Cistola, D.P. (1996) The NMR solution structure of intestinal fatty acid-binding protein complexed with palmitate:  Application of a novel distance geometry algorithm.  J. Mol. Biol. 264, 585-602.

Contact information
MS 668 Allied Health Deans Office, Health Sciences Building
600 Moye Boulevard
Greenville, NC 27834
Phone: 252.744.6012
Email: 
cistolad@ecu.edu