Mehul B. Patel, MD

Mehul B. Patel

Associate Professor, Division of Cardiology
Director of Structural and Adult Congenital Heart Disease

East Carolina Heart Institute at ECU
115 Heart Drive, Greenville, NC 27834

252-744-4400 (phone)
252-744-3987 (fax)


  • Structural and Adult Congenital Heart Disease
  • Interventional cardiology
  • Complex device implantations

Board Certifications

  • American Board of Internal Medicine
  • ABIM: Cardiovascular disease
  • ABIM: Adult congenital heart disease
  • ABIM: Interventional cardiology
  • ABIM: Clinical cardiac electrophysiology
  • International Board of Heart Rhythm Examiners
  • National Board of Echocardiography (Testamur)


  • Medical School: K. J. Somaiya Medical College, Mumbai, India, 1997
  • Residency: King Edward Memorial Hospital, Mumbai, India, 2002
  • Fellowship: Southern Railways Headquarters Hospital, Chennai, India, 2005
  • Fellowship: Sparrow Hospital, Michigan State University, Lansing, MI, 2008
  • Fellowship: Mount Sinai Medical Center, New York City, NY, 2009
  • Fellowship: Texas Children’s, Texas Heart Institute, Baylor College of Medicine, Houston, TX, 2013
  • Fellowship: Henry Ford Hospital, Detroit, MI, 2016

Professional Organizations

  • CHiP Network Professional: Co-Editor-in-Chief for CHiP Network journal watch


  1. Incidence and predictors of asymptomatic pericardial effusion after transcatheter closure of atrial septal defect.
    Wang J, Patel M, Xiao M, Xu Z, Jiang S, Sun X, Xu L, Wang H.
    EuroIntervention. 2016 Jun 12;12(2):e250-6. doi: 10.4244/EIJV12I2A39.
    PMID: 27290684
  2. Longitudinal strain of systemic right ventricle correlates with exercise capacity in adult with transposition of the great arteries after atrial switch.
    Ladouceur M, Redheuil A, Soulat G, Delclaux C, Azizi M, Patel M, Chatellier G, Legendre A, Iserin L, Boudjemline Y, Bonnet D, Mousseaux E; STARS Investigators.
    Int J Cardiol. 2016 Aug 15;217:28-34. doi: 10.1016/j.ijcard.2016.04.166. Epub 2016 May 3.
    PMID: 27179205
  3. Device-Detected Atrial Fibrillation-Perils and Pitfalls: An Update.
    Surapaneni P, Safadi A, Contractor T, Patel MB, Thakur RK.
    Cardiol Clin. 2016 May;34(2):299-306. doi: 10.1016/j.ccl.2015.12.007. Epub 2016 Mar 18. Review.
    PMID: 27150178
  4. Ventricular Tachycardia Ablation in Severe Heart Failure: An International Ventricular Tachycardia Ablation Center Collaboration Analysis.
    Tzou WS, Tung R, Frankel DS, Vaseghi M, Bunch TJ, Di Biase L, Tholakanahalli VN, Lakkireddy D, Dickfeld T, Saliaris A, Weiss JP, Mathuria N, Tedrow U, Afzal MR, Vergara P, Nagashima K, Patel M, Nakahara S, Vakil K, Burkhardt JD, Tseng CH, Natale A, Shivkumar K, Callans DJ, Stevenson WG, Della Bella P, Marchlinski FE, Sauer WH.
    Circ Arrhythm Electrophysiol. 2017 Jan;10(1). pii: e004494. doi: 10.1161/CIRCEP.116.004494.
    PMID: 28082527
  5. Sex and Catheter Ablation for Ventricular Tachycardia: An International Ventricular Tachycardia Ablation Center Collaborative Group Study.
    Frankel DS, Tung R, Santangeli P, Tzou WS, Vaseghi M, Di Biase L, Nagashima K, Tedrow U, Bunch TJ, Tholakanahalli VN, Dendi R, Reddy M, Lakkireddy D, Dickfeld T, Weiss JP, Mathuria N, Vergara P, Patel M, Nakahara S, Vakil K, Sauer WH, Callans DJ, Natale A, Stevenson WG, Della Bella P, Shivkumar K, Marchlinski FE.
    JAMA Cardiol. 2016 Nov 1;1(8):938-944. doi: 10.1001/jamacardio.2016.2361.
    PMID: 27556589
  6. CMR assessment of the left ventricle apical morphology in subjects with unexplainable giant T-wave inversion and without apical wall thickness ≥15 mm.
    Wu B, Lu M, Zhang Y, Song B, Ling J, Huang J, Yin G, Lan T, Dai L, Song L, Jiang Y, Wang H, He Z, Lee J, Yong HS, Patel MB, Zhao S.
    Eur Heart J Cardiovasc Imaging. 2017 Feb;18(2):186-194. doi: 10.1093/ehjci/jew045. Epub 2016 Mar 29.
    PMID: 27025513
  7. Percutaneous Melody valve implantation for tricuspid valve regurgitation with very large annulus: the diabolo-shaped bridge for valve-in-stent technique.
    Malekzadeh-Milani S, Patel M, Boudjemline Y.
    EuroIntervention. 2016 Apr 20;11(13):1563. doi: 10.4244/EIJY15M07_09. No abstract available.
    PMID: 26477644
  8. Implantable atrial flow regulator for severe, irreversible pulmonary arterial hypertension.
    Patel MB, Samuel BP, Girgis RE, Parlmer MA, Vettukattil JJ.
    EuroIntervention. 2015 Oct;11(6):706-9. doi: 10.4244/EIJY15M07_08.
    PMID: 26477643
  9. Safety and Feasibility of Open Chest Epicardial Mapping and Ablation of Ventricular Tachycardia During the Period of Left Ventricular Assist Device Implantation.
    Patel M, Rojas F, Shabari FR, Simpson L, Cohn W, Frazier OH, Mallidi H, Cheng J, Mathuria N.
    J Cardiovasc Electrophysiol. 2016 Jan;27(1):95-101. doi: 10.1111/jce.12839. Epub 2015 Nov 4.
    PMID: 26377813
  10. Selective propensity of bovine jugular vein material to bacterial adhesions: An in-vitro study.
    Jalal Z, Galmiche L, Lebeaux D, Villemain O, Brugada G, Patel M, Ghigo JM, Beloin C, Boudjemline Y.
    Int J Cardiol. 2015 Nov 1;198:201-5. doi: 10.1016/j.ijcard.2015.07.004. Epub 2015 Jul 6.
    PMID: 26173058
  11. Freedom from recurrent ventricular tachycardia after catheter ablation is associated with improved survival in patients with structural heart disease: An International VT Ablation Center Collaborative Group study.
    Tung R, Vaseghi M, Frankel DS, Vergara P, Di Biase L, Nagashima K, Yu R, Vangala S, Tseng CH, Choi EK, Khurshid S, Patel M, Mathuria N, Nakahara S, Tzou WS, Sauer WH, Vakil K, Tedrow U, Burkhardt JD, Tholakanahalli VN, Saliaris A, Dickfeld T, Weiss JP, Bunch TJ, Reddy M, Kanmanthareddy A, Callans DJ, Lakkireddy D, Natale A, Marchlinski F, Stevenson WG, Della Bella P, Shivkumar K.
    Heart Rhythm. 2015 Sep;12(9):1997-2007. doi: 10.1016/j.hrthm.2015.05.036. Epub 2015 May 30.
    PMID: 26031376
  12. Transcatheter intervention in cor triatriatum sinister.
    Patel MB, Samuel BP, Berjaoui WK, Girgis RE, Vettukattil JJ.
    Can J Cardiol. 2015 Jun;31(6):819.e3-4. doi: 10.1016/j.cjca.2015.01.036. Epub 2015 Feb 4.
    PMID: 26022992
  13. Maternal and fetal outcomes of pregnancy with Fontan circulation: A multicentric observational study.
    Gouton M, Nizard J, Patel M, Sassolas F, Jimenez M, Radojevic J, Mathiron A, Amedro P, Barre E, Labombarda F, Vaksmann G, Chantepie A, Le Gloan L, Ladouceur M.
    Int J Cardiol. 2015;187:84-9. doi: 10.1016/j.ijcard.2015.03.344. Epub 2015 Mar 23.
    PMID: 25828319
  14. Neuronally released vasoactive intestinal polypeptide alters atrial electrophysiological properties and may promote atrial fibrillation.
    Xi Y, James Chao ZY, Yan W, Abbasi S, Yin X, Mathuria N, Patel M, Fan C, Sun J, Wu G, Wang S, Elayda M, Gao L, Wehrens XH, Lin SF, Cheng J.
    Heart Rhythm. 2015 Jun;12(6):1352-61. doi: 10.1016/j.hrthm.2015.03.003. Epub 2015 Mar 5.
    PMID: 25748673
  15. Safety and effectiveness of compassionate use of LARIAT® device for epicardial ligation of anatomically complex left atrial appendages.
    Patel MB, Rasekh A, Shuraih M, Chelu MG, Bartlett T, Mathuria N, Naeini P, Strickland J, Massumi A, Razavi M, Cheng J.
    J Interv Card Electrophysiol. 2015 Jan;42(1):11-9. doi: 10.1007/s10840-014-9963-2. Epub 2015 Jan 17.
    PMID: 25595627
  16. Percutaneous pulmonary valve endocarditis: incidence, prevention and management.
    Patel M, Malekzadeh-Milani S, Ladouceur M, Iserin L, Boudjemline Y.
    Arch Cardiovasc Dis. 2014 Nov;107(11):615-24. doi: 10.1016/j.acvd.2014.07.052. Epub 2014 Oct 16. Review.
    PMID: 25445753
  17. Incidence and predictors of Melody® valve endocarditis: a prospective study.
    Malekzadeh-Milani S, Ladouceur M, Patel M, Boughenou FM, Iserin L, Bonnet D, Boudjemline Y.
    Arch Cardiovasc Dis. 2015 Feb;108(2):97-106. doi: 10.1016/j.acvd.2014.09.003. Epub 2014 Oct 30.
    PMID: 25445752
  18. Predictors and outcomes of right ventricular outflow tract conduit rupture during percutaneous pulmonary valve implantation: a multicentre study.
    Boudjemline Y, Malekzadeh-Milani S, Patel M, Thambo JB, Bonnet D, Iserin L, Fraisse A.
    EuroIntervention. 2016 Jan 22;11(9):1053-62. doi: 10.4244/EIJY14M09_06.
    PMID: 25244126
  19. Novel method of surgical preparation for transcatheter completion of Fontan circulation: creation of an extracardiac pathway.
    Boudjemline Y, Malekzadeh-Milani S, Van Steenberghe M, Bögli Y, Patel M, Gaudin R, Bonnet D, Gerelli S.
    Arch Cardiovasc Dis. 2014 Jun-Jul;107(6-7):371-80. doi: 10.1016/j.acvd.2014.05.003. Epub 2014 Jun 24.
    PMID: 24973114
  20. Hyperacute flash pulmonary oedema after transcatheter pulmonary valve implantation: The melody of an overwhelmed left ventricle.
    Alsulami G, Patel M, Malekzadeh-Milani S, Bonnet D, Boudjemline Y.
    Arch Cardiovasc Dis. 2014 Apr;107(4):219-24. doi: 10.1016/j.acvd.2014.03.007. Epub 2014 May 2.
    PMID: 24793996
  21. Folded Melody valve technique for complex right ventricular outflow tract.
    Malekzadeh-Milani S, Patel M, Boudjemline Y.
    EuroIntervention. 2014 Feb;9(10):1237-40. doi: 10.4244/EIJV9I10A207.
    PMID: 24561739
  22. Atriopulmonary Fontan spontaneous echo contrast improved after cardioversion.
    Lam WW, Patel MB, Rodriguez FH 3rd, Parekh DR, Franklin WJ.
    Tex Heart Inst J. 2014 Feb;41(1):100-2. doi: 10.14503/THIJ-13-3292. No abstract available.
    PMID: 24512415
  23. Assessment of adequate safety margin using single coupling interval-upper limit of vulnerability test.
    Patel MB, Pandya K, Thakur RK.
    Pacing Clin Electrophysiol. 2014 Jan;37(1):95-103. doi: 10.1111/pace.12251. Epub 2013 Aug 26.
    PMID: 24033830
  24. Patent ductus arteriosus stenting (transcatheter Potts shunt) for palliation of suprasystemic pulmonary arterial hypertension: a case series.
    Boudjemline Y, Patel M, Malekzadeh-Milani S, Szezepanski I, Lévy M, Bonnet D.
    Circ Cardiovasc Interv. 2013 Apr;6(2):e18-20. doi: 10.1161/CIRCINTERVENTIONS.112.000091. No abstract available.
    PMID: 23591423
  25. Impact of right ventricular outflow tract size and substrate on outcomes of percutaneous pulmonary valve implantation.
    Boudjemline Y, Sarquella-Brugada G, Kamache I, Patel M, Ladouceur M, Bonnet D, Boughenou FM, Fraisse A, Iserin L.
    Arch Cardiovasc Dis. 2013 Jan;106(1):19-26. doi: 10.1016/j.acvd.2012.09.005. Epub 2012 Dec 25.
    PMID: 23374968
  26. Snare coupling of the pre-pectoral pacing lead delivery catheter to the femoral transseptal apparatus for endocardial cardiac resynchronization therapy : mid-term results.
    Patel MB, Worley SJ.
    J Interv Card Electrophysiol. 2013 Apr;36(3):209-16. doi: 10.1007/s10840-012-9734-x. Epub 2012 Nov 21.
    PMID: 23179917
  27. Feasibility of creating a novel animal heart model to test transcatheter techniques for a cavocaval connection that mimics a Fontan completion.
    Gerelli S, Van Steenberghe M, Patel M, Van Aerschot I, Boudjemline Y.
    J Thorac Cardiovasc Surg. 2013 Aug;146(2):408-12. doi: 10.1016/j.jtcvs.2012.09.059. Epub 2012 Oct 23.
    PMID: 23102683
  28. Outcomes and safety of transcatheter pulmonary valve replacement in patients with large patched right ventricular outflow tracts.
    Boudjemline Y, Brugada G, Van-Aerschot I, Patel M, Basquin A, Bonnet C, Legendre A, Bonnet D, Iserin L.
    Arch Cardiovasc Dis. 2012 Aug-Sep;105(8-9):404-13. doi: 10.1016/j.acvd.2012.05.002. Epub 2012 Jul 17.
  29. Feasibility of transcatheter techniques for intracardiac and extracardiac cavocaval connection in principle for Fontan completion in chronic animal models.
    Boudjemline Y, Gerelli S, Van Steenberghe M, Patel M, Malekzadeh-Milani S, Bonnet D.
    Eur J Cardiothorac Surg. 2013 Apr;43(4):856-60. doi: 10.1093/ejcts/ezs451. Epub 2012 Aug 31.
    PMID: 22942361
  30. Branch pulmonary artery jailing with a bare metal stent to anchor a transcatheter pulmonary valve in patients with patched large right ventricular outflow tract.
    Boudjemline Y, Legendre A, Ladouceur M, Boughenou MF, Patel M, Bonnet D, Iserin L.
    Circ Cardiovasc Interv. 2012 Apr;5(2):e22-5. doi: 10.1161/CIRCINTERVENTIONS.112.968610. No abstract available.
    PMID: 22511743
  31. Atypical malignant late infective endocarditis of Melody valve.
    Patel M, Iserin L, Bonnet D, Boudjemline Y.
    J Thorac Cardiovasc Surg. 2012 Apr;143(4):e32-5. doi: 10.1016/j.jtcvs.2012.01.006. Epub 2012 Jan 27. No abstract available.
    PMID: 22284627
  32. Outcomes of patients discharged the same day following percutaneous coronary intervention.
    Patel M, Kim M, Karajgikar R, Kodali V, Kaplish D, Lee P, Moreno P, Krishnan P, Sharma SK, Kini AS.
    JACC Cardiovasc Interv. 2010 Aug;3(8):851-8. doi: 10.1016/j.jcin.2010.05.010.
    PMID: 20723858
  33. High defibrillation threshold: the science, signs and solutions.
    Jacob S, Pidlaoan V, Singh J, Bharadwaj A, Patel MB, Carrillo A.
    Indian Pacing Electrophysiol J. 2010 Jan 7;10(1):21-39.
    PMID: 20084193
  34. Characteristics of telemetry interference with pacemakers caused by digital media players.
    Shah AJ, Brunett JD, Thaker JP, Patel MB, Liepa VV, Jongnarangsin K, Thakur RK.
    Pacing Clin Electrophysiol. 2010 Jun 1;33(6):712-20. doi: 10.1111/j.1540-8159.2009.02672.x. Epub 2010 Jan 5.
    PMID: 20059718
  35. Do media players cause interference with pacemakers?
    Thaker JP, Patel MB, Shah AJ, Liepa VV, Brunett JD, Jongnarangsin K, Gardiner JC, Thakur R.
    Clin Cardiol. 2009 Nov;32(11):653-7. doi: 10.1002/clc.20625.
    PMID: 19938055
  36. Cor triatriatum sinister with bicuspid aortic valve: a rare association.
    Dhoble A, Patel M, Shah I, Thakur RK, Abela GS.
    Clin Cardiol. 2009 Nov;32(11):E88. doi: 10.1002/clc.20368. No abstract available.
    PMID: 19816972
  37. Neurotoxic and cardiotoxic effects of cocaine and ethanol.
    Farooq MU, Bhatt A, Patel M.
    J Med Toxicol. 2009 Sep;5(3):134-8.
    PMID: 19655286
  38. Relation of porphyria to atrial fibrillation.
    Dhoble A, Patel MB, Abdelmoneim SS, Puttarajappa C, Abela GS, Bhatt DL, Thakur RK.
    Am J Cardiol. 2009 Aug 1;104(3):373-6. doi: 10.1016/j.amjcard.2009.03.043. Epub 2009 Jun 6.
    PMID: 19616670
  39. Predictors of hemodynamic compromise with propofol during defibrillator implantation: a single center experience.
    Pandya K, Patel MB, Natla J, Dhoble A, Habetler T, Holliday J, Janes R, Punnam SR, Gardiner JC, Thakur RK.
    J Interv Card Electrophysiol. 2009 Aug;25(2):145-51. doi: 10.1007/s10840-008-9355-6. Epub 2009 Mar 5.
    PMID: 19263205
  40. Cardiac steatosis and myocardial dysfunction.
    Dhoble A, Patel MB.
    J Am Coll Cardiol. 2009 Feb 17;53(7):636; author reply 636-7. doi: 10.1016/j.jacc.2008.10.042. No abstract available.
    PMID: 19215842
  41. A media player causes clinically significant telemetry interference with implantable loop recorders.
    Thaker JP, Patel MB, Shah AJ, Liepa VV, Jongnarangsin K, Thakur RK.
    J Interv Card Electrophysiol. 2009 Mar;24(2):99-103. doi: 10.1007/s10840-008-9332-0. Epub 2009 Jan 16.
    PMID: 19148732
  42. Guillain-Barré Syndrome with asystole requiring permanent pacemaker: a case report.
    Patel MB, Goyal SK, Punnam SR, Pandya K, Khetarpal V, Thakur RK.
    J Med Case Rep. 2009 Jan 6;3:5. doi: 10.1186/1752-1947-3-5.
    PMID: 19126210
  43. Cocaine and alcohol: a potential lethal duo.
    Patel MB, Opreanu M, Shah AJ, Pandya K, Bhadula R, Abela GS, Thakur RK.
    Am J Med. 2009 Jan;122(1):e5-6. doi: 10.1016/j.amjmed.2008.09.017. No abstract available.
    PMID: 19114159
  44. Heart rate variability in a man with anorexia.
    Dhoble A, Puttarajappa C, Patel MB, Thakur RK.
    Am J Med. 2008 Dec;121(12):e5-6. doi: 10.1016/j.amjmed.2008.07.020. No abstract available.
    PMID: 19028188
  45. Electromagnetic interference in an implantable loop recorder caused by a portable digital media player.
    Thaker JP, Patel MB, Jongnarangsin K, Liepa VV, Castellani M, Thakur RK.
    Pacing Clin Electrophysiol. 2008 Oct;31(10):1345-7. doi: 10.1111/j.1540-8159.2008.01188.x.
    PMID: 18811818
  46. Reel syndrome-not a twiddler variant.
    Patel MB, Pandya K, Shah AJ, Lojewski E, Castellani MD, Thakur R.
    J Interv Card Electrophysiol. 2008 Dec;23(3):243-6. doi: 10.1007/s10840-008-9288-0. Epub 2008 Aug 8.
    PMID: 18688700
  47. Electromagnetic interference with pacemakers caused by portable media players.
    Thaker JP, Patel MB, Jongnarangsin K, Liepa VV, Thakur RK.
    Heart Rhythm. 2008 Apr;5(4):538-44. doi: 10.1016/j.hrthm.2008.01.028. Epub 2008 Jan 29.
    PMID: 18329961
  48. Hemodynamic collapse during left ventricular lead implantation.
    Punnam SR, Holiday J, Janes R, Touma R, Li H, Patel M, Abela GS, Thakur RK.
    Pacing Clin Electrophysiol. 2007 Sep;30(9):1112-5.
    PMID: 17725754
  49. Pacemaker interference with an iPod.
    Patel MB, Thaker JP, Punnam S, Jongnarangsin K.
    Heart Rhythm. 2007 Jun;4(6):781-4. Epub 2007 Mar 1. No abstract available.
    PMID: 17556203
  50. Post Glenn shunt: how to pace?
    Patel MB, Punnam SR, Gupta AK, Murthy KS, Thakur RK.
    Pacing Clin Electrophysiol. 2007 May;30(5):672-4. No abstract available.
    PMID: 17461878