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The Brody School of Medicine at East Carolina University
The Department of Internal Medicine

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Division of Pulmonary and Critical Care Medicine


Recent Publications

1.      Culver DA, Barna BP, Raychaudhuri B, Bonfield TL, Abraham S, Malur A, Farver CF, Kavuru MS, Thomassen MJ.  Peroxisome proliferator-activated receptor gamma activity is deficient in alveolar macrophages in pulmonary sarcoidosis. Am J Respir Cell Mol Biol 2004;30:1-5.

2.     Culver DA, Thomassen MJ, Kavuru MS.. Pulmonary sarcoidosis: new genetic clues and ongoing treatment controversies. Cleve Clin J Med 2004;71:88-106.

3.      Raychaudhuri B, Abraham S, Bonfield TL, Malur A, Deb A, DiDonato JA, Kavuru MS, Thomassen MJ. Surfactant blocks lipopolysaccharide signaling by inhibiting both mitogen-activated protein and IkappaB kinases in human alveolar macrophages. Am J Respir Cell Mol Biol 2004;30:228-232.

4.       Bonfield TL, Yen-Lieberman B, Kavuru MS, Thomassen MJ.  Multiplexed particle-based anti-GM-CSF assay: a pulmonary diagnostic test.  Clin Diag Lab Immunol 2005 12:821-824.

5.       Venkateshiah SB, Thomassen MJ, Kavuru MS.  Pulmonary alveolar proteinosis.  Treat Respir Med 2004;3(4):217-227.

6.        Bonfield TL, Nejimole J, Malur A, Barna BP, Culver DA, Kavuru, MS, Thomassen MJ. Elevated monocyte chemotactic proteins 1, 2, and 3 in pulmonary alveolar proteinosis (PAP) are associated with chemokine receptor suppression.  Clin Immunol 2005;114:79-85.

7.       Meaney S, Bonfield TL, Hansson M, Babiker A, Kavuru MS, Thomassen MJ.  Serum cholestenoic acid as a potential marker of pulmonary cholesterol homeostasis:  Elevated levels in patients with pulmonary alveolar proteinosis. J Lipid Res 2004;45(12):2354-2360.

8.      Kavuru MS, Bonfield TR, Thomassen MJ.  Pulmonary Alveolar Proteinosis.  In: Murray and Nadel’s Textbook of Respiratory Medicine, eds Mason RJ, Broaddus VC, Murray JF, Nadel JA. 2005.

9.      Kobayashi M, Thomassen MJ, Rambasek T, Bonfield TL, Raychaudhuri B, Malur A, Winkler AR, Barna BP, Goldman SJ, Kavuru MS An inverse relationship between PPARγ and allergic airway inflammation in an allergen challenge model.  Ann Allergy Immunol 2005 (in press). 

10.     Follettie MT, Diesl V, Cai J, Wei S-Q, Wang I-M, Wood N, Malur A, Raychaudhuri B, Jiao A, Sypek JP, Williams CMM, Owens CA, Dorner AJ, Goldman SJ, Kavuru M, Kobayashi M, Thomassen MJ.  Regulation of MMP-12 expression by allergen challenge in the asthmatic response.  Submitted J Clin Invest.

11.     Wu J, Kobayashi M, Sousa E, Liu W, Cai J, Goldman S, Dorner A, Projan S, Kavuru M, Thomassen MJ.  Differential proteomic analysis of bronchoalveolar lavage fluid in asthmatics following segmental antigen challenge.  Mol Cell Proteomics 2005;4:1251-1264.

12.     Bonfield TL, Barna BP, John N, Malur A, Culver DA, Kavuru MS, Thomassen MJ. Suppression of activin A in autoimmune lung disease associated with anti-GM-CSF. J Autoimmunity 2005 (in press).

13.     Barna BP, Culver DA, Susamma A, Malur A, Bonfield TL, John N, Farver CF, Drazba JA, Raychaudhuri G, Kavuru MS, Thomassen MJ. Depressed peroxisome proliferator-activated receptor gamma (PPARg) is indicative of severe pulmonary sarcoidosis: possible involvement of interferon gamma (IFN-g). Sarcoidosis, Vasculitis and Diffuse Lung Disease Journal 2005 (in press).

14.     Bonfield TL, Swaisgood CM, Barna BP, Farver CF, Kavuru MS, Thomassen MJ. Elevated gelatinase activity in pulmonary alveolar proteinosis: role of macrophage-colony stimulating factor. J Leukoc Biol 2006;79:133-9.