Sonja Karin Bareiss, PhD, PT
Assistant Professor
College of Allied Health Sciences
Health Sciences Building, 2505G, Lab 3400-1
Greenville, NC 27858
252.744.6243 office
252.744.6250 lab


Neuroscience Laboratory Website

Professional Interest

My clinical interests are in the area of chronic pain following injury and disease. Research focuses on recovery from chronic pain and sensory abnormalities following central and peripheral nervous system injury.

  • Molecular and cellular mechanisms involved in pain/sensory dysfunction following spinal cord injury
  • Neuroprotective effect of exercise in recovery from chronic pain and improved cognitive function following central nervous system injury

Education History

B.S. Biology
Rockhurst University  

Masters in Physical Therapy
Rockhurst University  

Ph.D. Anatomy and Cell Biology
East Carolina University                                     

Selected Publications

S. K. Bareiss and Q. Lu. δ-Catenin: A new member of the glycogen synthase kinase-3b signaling complex that promotes b-catenin turnover in neurons. Journal of Neuroscience Research, 2010 Aug 15; 88(11):2350-63.  

M. Oh, H. Kim, I. Yang, J. Park, W. Cong, M. Baek, S. K.  Bareiss, H. Ki, Q. Lu, J. No, I. Kwon, J. Choi, and  K. Kim , GSK-3 phosphorylates δ-catenin and negatively regulates its stability via ubiquitination/proteosome-mediated proteolysis. Journal of Biological Chemistry, 2009 Oct 16; 284(42): 28579-89.  

K. Kwonseop, M. Oh, H. Ki, T. Wang, S. Bareiss, M. Fini, D. Li, and Q. Lu, Identification of E2F1 as a positive transcriptional regulator for d-catenin, Biochemical and Biophysical Research Communications, 2008 May 2; 369(2):414-20.  

J. Kim*, S. K. Bareiss*, K. Kim, R. Tatum, J. Han, Y. Jin, H. Kim, Q. Lu, and K. Kim, Presenilin-1 inhibits δ-catenin-induced cellular branching and promotes δ-catenin processing and turnover. Biochemical and Biophysical Research Communications. 2006 Dec; 351(4):903-8.      


PTHE 8101 Neuroscience (Course director)
PTHE 8201 Electrotherapeutic Diagnosis and Treatment (Course director)
PTHE 8912 Pain Mechanisms and Treatment (Course director)
PTHE 8906 & 8907 Research Concentration
PTHE 8104 Pharmacological Agents and Pathological Processes (Lecturer)

Notable student achievements from the lab:

  • Angela Korleski presented her findings at the Southern Regional Honors Council Conference, Louisville, KY, April 2013.
  • Angela Korleski, Best Undergraduate Poster Presentation at ECU Research and Creative Activity Week, March 2012 & 2013, completed Senior Honors Biology Thesis
  • Morgan Haskins, Undergraduate Research and Creative Activity Award recipient, Spring 2013, $900; completed Senior Honors Thesis.
  • Angela Korleski, Undergraduate Research and Creative Activity Award recipient, Spring 2012, $1450.
  • Shelley Burgess, Undergraduate Research and Creative Activity Award recipient, Spring 2012, $983.
    • Enrolled as DPT student Arkansas State University, Class of 2015
  • Tiffany Lee, Undergraduate Research and Creative Activity Award recipient, Spring 2011, $1500.
    • Enrolled in ECU Brody School of Medicine, Class 2015
  • Kristin Hernandez, DPT, 2nd place Poster Presentation Award, North Carolina Physical Therapy Association State Conference, October 2010.
Professional Affiliations
  • American Physical Therapy Association (APTA)
  • Society for Neuroscience
  • International Association for the Study of Pain
  • East Carolina Chapter of the Society of Neuroscience – Secretary
  • The Wooten Laboratory of Alzheimer's Disease and Neurodegenerative Diseases Research
Current and Previous Funding:
  • Alzheimer's North Carolina, Inc, A Multidisciplinary Approach to Fight Senior Dementia: The Wooten Laboratory for Alzheimer's and Neurodegenerative Diseases Research
  • Wooten Laboratory for Alzheimer's and Neurodegenerative Disease Research
Laboratory members:
  • Lindsey Cannon, DPT student
  • Blaire Conner, Undergraduate Exercise Physiology
  • Nicole Corrieri, Undergraduate Neuroscience
  • James Jackson, Undergraduate Neuroscience
  • Tyler Johnston, DPT student
  • Rebecca Kretchman, DPT student
  • Katie Thomas, DPT student
  • Kathryn Tune, DPT student
  • Miranda Shipman, Undergraduate Neuroscience
  • Alison Sloan, DPT student
  • Katrina Sumcad, DPT student


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