Sonja Karin Bareiss, PhD, PT
College of Allied Health Sciences
Health Sciences Building, 2505G, Lab 3400-1
Greenville, NC 27858
My clinical interests are in the area of chronic pain following injury and disease. Research focuses on recovery from chronic pain and sensory abnormalities following central and peripheral nervous system injury.
- Molecular and cellular mechanisms involved in pain/sensory dysfunction following spinal cord injury
- Neuroprotective effect of exercise in recovery from chronic pain and improved cognitive function following central nervous system injury
Masters in Physical Therapy
Ph.D. Anatomy and Cell Biology
East Carolina University
S.K. Bareiss, M. Gwaltney*, K. Hernandez*, T. Lee*, and K.L. Brewer. Excitotoxic spinal cord injury induced dysesthesias are associated with enhanced intrinsic growth of sensory neurons, Neuroscience Letters, 2013 May 10; 542:113-7 PMID 23500027. *Denotes student authors
S. K. Bareiss and Q. Lu. δ-Catenin: A new member of the glycogen synthase kinase-3b signaling complex that promotes b-catenin turnover in neurons. Journal of Neuroscience Research, 2010 Aug 15; 88(11):2350-63.
M. Oh, H. Kim, I. Yang, J. Park, W. Cong, M. Baek, S. K. Bareiss, H. Ki, Q. Lu, J. No, I. Kwon, J. Choi, and K. Kim , GSK-3 phosphorylates δ-catenin and negatively regulates its stability via ubiquitination/proteosome-mediated proteolysis. Journal of Biological Chemistry, 2009 Oct 16; 284(42): 28579-89.
K. Kwonseop, M. Oh, H. Ki, T. Wang, S. Bareiss, M. Fini, D. Li, and Q. Lu, Identification of E2F1 as a positive transcriptional regulator for d-catenin, Biochemical and Biophysical Research Communications, 2008 May 2; 369(2):414-20.
J. Kim*, S. K. Bareiss*, K. Kim, R. Tatum, J. Han, Y. Jin, H. Kim, Q. Lu, and K. Kim, Presenilin-1 inhibits δ-catenin-induced cellular branching and promotes δ-catenin processing and turnover. Biochemical and Biophysical Research Communications. 2006 Dec; 351(4):903-8.
PTHE 8101 Neuroscience (Course director)
PTHE 8201 Electrotherapeutic Diagnosis and Treatment (Course director)
PTHE 8912 Pain Mechanisms and Treatment (Course director)
PTHE 8906 & 8907 Research Concentration
PTHE 8104 Pharmacological Agents and Pathological Processes (Lecturer)
Notable student achievements from the lab:
- Alyssa DaVolio, Undergraduate Research and Creative Activity Award recipient, Fall 2013, $1.125.
- Angela Korleski presented her findings at the Southern Regional Honors Council Conference, Louisville, KY, April 2013.
- Angela Korleski, Best Undergraduate Poster Presentation at ECU Research and Creative Activity Week, March 2012 & 2013, completed Senior Honors Biology Thesis
- Morgan Haskins, Undergraduate Research and Creative Activity Award recipient, Spring 2013, $900; completed Senior Honors Thesis.
- Angela Korleski, Undergraduate Research and Creative Activity Award recipient, Spring 2012, $1450.
- Shelley Burgess, Undergraduate Research and Creative Activity Award recipient, Spring 2012, $983.
- Enrolled as DPT student Arkansas State University, Class of 2015
- Tiffany Lee, Undergraduate Research and Creative Activity Award recipient, Spring 2011, $1500.
- Enrolled in ECU Brody School of Medicine, Class 2015
- Kristin Hernandez, DPT, 2nd place Poster Presentation Award, North Carolina Physical Therapy Association State Conference, October 2010.
- American Physical Therapy Association (APTA)
- Society for Neuroscience
- International Association for the Study of Pain
- East Carolina Chapter of the Society of Neuroscience – Secretary
- The Wooten Laboratory of Alzheimer's Disease and Neurodegenerative Diseases Research
Current and Previous Funding:
- Alzheimer's North Carolina, Inc, A Multidisciplinary Approach to Fight Senior Dementia: The Wooten Laboratory for Alzheimer's and Neurodegenerative Diseases Research
- Wooten Laboratory for Alzheimer's and Neurodegenerative Disease Research
Lindsey Cannon, DPT student
Blaire Conner, Undergraduate Exercise Physiology
Nicole Corrieri, Undergraduate Neuroscience
James Jackson, Undergraduate Neuroscience
Tyler Johnston, DPT student
Rebecca Kretchman, DPT student
Katie Thomas, DPT student
Kathryn Tune, DPT student
Miranda Shipman, Undergraduate Neuroscience
Alison Sloan, DPT student
Katrina Sumcad, DPT student