Professional Interest
Research interests are in the areas of diabetes, obesity, and exercise including:
- mechanisms of skeletal muscle glucose transporter gene regulation
- hormones related to satiety and insulin sensitivity
Education History
Ph.D. Biochemistry
University of Kansas, 2000
M.S.Ed. Exercise Physiology
University of Kansas, 1988
B.A. Physical Education (concentration - Exercise Science)
Washburn University, 1985
Selected Publications
Wright DC, Geiger PC, Han DH, Jones TE, Holloszy JO (2007) Calcium induces increases in peroxisome proliferator-activated receptor γ coactivator-1α and mitochondrial biogenesis by a pathway leading to p38 mitogen-activated protein kinase activation. J Biol Chem 282:18793-18799.
Wright DC, Han DH, Garcia-Roves PM, Geiger PC, Jones TE, Holloszy JO (2007) Exercise-induced mitochondrial biogenesis begins before the increase in muscle PGC-1α expression. J Biol Chem 282:194-199
Garcia-Roves PM, Jones TE, Otan K, Han DH, Holloszy JO, (2005) Calcineurin does not mediate exercise-induced increase in muscle GLUT4. Diabetes 54:624-628
Garcia-Roves PM, Han DH, Song Z, Jones TE, Hucker KA, Holloszy JO (2003) Prevention of glycogen supercompensation prolongs the increase in muscle GLUT4 after exercise. Am J Physiol Endocrinol Metab 285:E729-736
Baar K, Song Z, Semenkovich CF, Jones TE, Han DH, Nolte L, Ojuka EO, Chen M, and Holloszy, JO (2003) Skeletal muscle overexpression of nuclear respiratory factor 1 increases glucose transport capacity. FASEB J 17:1666-1673
Ojuka EO, Jones TE, Han D-H, Chen M, and Holloszy JO (2003) Raising Ca2+ in L6 myotubes mimics effects of exercise on mitochondrial biogenesis in muscle. FASEB J 17:675-681
Jones TE, Baar K, Ojuka E, Chen M, and Holloszy JO (2003) Exercise induces an increase in muscle UCP3 as a component of the increase in mitochondrial biogenesis. Am J Physiol Endocrinol Metab 284:E96-101
Baar K, Wende AR, Jones TE, Marison M, Nolte LA, Chen M, Kelly DP, and Holloszy JO (2002) Adaptations of muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB J 16:1879-86
Ojuka EO, Jones TE, Han DH, Chen M, Wamhoff BR, Sturek M, Hollosz, JO (2002) Intermittent increases in cytosolic Ca2+ stimulate mitochondrial biogenesis in muscle cells. Am J Physiol Endocrinol Metab 283:E1040-E1045
Fisher JS, Nolte LA, Kawanaka K, Han DH, Jones TE, and Holloszy JO (2002) Glucose transport rate and glycogen synthase activity both limit skeletal muscle glycogen accumulation. Am J Physiol Endocrinol Metab 282:E1214-E1221
Ojuka EO, Jones TE, Nolte LA, Chen M, Wamhoff BR, Sturek M, Holloszy JO (2002) Regulation of GLUT 4 biogenesis in muscle: evidence for involvement of AMPK and Ca2+. Am J Physiol Endocrinol Metab 282:E1008-E1013
