Employment History
Research Fellow, Biochemistry and Molecular Biology Department, China Agricultural University, Beijing, China, 1995-1997
Associate Professor, Biochemistry and Molecular Biology Department, China Agricultural University, Beijing, China, 1997-2000
Research Associate, Department of Pharmacology, The Brody School of Medicine at ECU, 2000-2001
Research Associate, Department of Anatomy and Cell Biology, The Brody School of Medicine at ECU, 2001-present
Teaching Experience
Control of the Gene Expression, Beijing Agricultural University, 1997-2000
Biomembrane and Intracellular Transports of Cell, Beijing Agricultural University, 1996-2000
Grants and Research Support
Establish high-level expression eukaryotis system by using DHFR-deficient CHO cells, Beijing Agriculture University, ¥50000, 1995-1997, Co-Principal Investigator.
The mechanism by which hormones regulate β-casein gene transcription, China Nature Science Foundation, ¥80000, 1996 to August 1999, Principal Investigator.
Motor interaction in the testis, East Carolina University, $5000, 2001-2002, Principal Investigator.
Professional Societies
The American Society for Cell Biology, 2000-present
The American Association for the Advancement of Science, 2001-2003
Research Activities and Interests
Molecular cell biology has been an import part of my research. I am interested in several cellular processes including cell division, intracellular transport, polarity, morphogenesis and motility. Recent years, I am focusing on one group of kinesin motor protein, named c-terminal kinesin motor protein. Our research indicates that the function of these proteins is related to spindle formation and vesicle transport. The mechanism by which motors and microtubule mediate these all-cellular processes is being further investigated.
Publications
Zhang, Y. and A.O. Sperry. 2004. Comparative analysis of two C-terminal kinesin motor proteins: KIFC1 and KIFC5A. Cell Motility and the Cytoskeleton. 58(4):213-230.
Zakharov, I.A., I. G. Moiseyeva, A. A. Nikiforov, and Y. Zhang. 1999. Morphological comparison of old Russian chicken breeds with representatives of Mediterranean, Chinese and ancestral breeds. SABRAO journal of Breeding and Genetics. 31(1):9-15.
Abstracts
Sperry, Ann O., Wanxi Wang, and Yuguo Zhang. 2004. The KIFC Family of Microtubule Motors: Divergence poles in Mammalian Spermatogenesis. (Submit to meeting)
Zhang, Y. and A.O. Sperry. 2002. Comparative Analysis of Two Related C-Terminal Motors. American Society for Cell Biology Annual meeting (42)
Zhang, Y. and Ann O. Sperry. 2001. Functional Characterization of Kinesin related Protein KIFC5A. Abstract for 41st Annual Meeting, The American Society for Cell Biology.
Zhang Yuguo and G.E. Sulimova. 1996. The analysis of polymorphism of BoLA-DQB gene of cattle by PCR RFLP. The First International Conference on Molecular-Genetics Marker of Animal. Ukraine, Kiew. 63-73.
