Address:
Brody School of Medicine at East Carolina University
600 Moye Boulevard
Edward Nelson Warren Life Sciences Building
Room # LSB 177
Greenville, NC 27834
Fax: 252.744.2687
Telephone: 252.744.3552
E-mail: kypsona@ecu.edu
Education: 1981-5 Great Neck North Senior High School Diploma
Great Neck, NY
1985-9 Columbia College BA, History
New York City, NY
1989-93 Columbia College of Physicians&Surgeons MD
New York City, NY
Professional Training:
1984-8 Cardiovascular Surgical Assistant, Division of Cardiothoracic Surgery, University Hospital of Zurich, Zurich, Switzerland.
1988-9 Emergency Medical Technician, New York, N.Y.
1988-90 Laboratory Research Assistant, Department of Anesthesiology, Columbia College of Physicians&Surgeons,
New York, N.Y.
1993-4 Intern, Department of General Surgery, Duke University Medical Center, Durham, N.C.
1994-5 Junior Assistant Resident, Department of General Surgery, Duke University Medical Center, Durham, N.C.
1995-7 Research Fellow, Division of Cardiothoracic Surgery, Duke University Medical Center, Durham, N.C.
1996-7 Instructor in Surgery and Course Director, Physician Assistant Program, Department of Surgery, Duke University Medical Center, Durham, N.C.
1997-9 Senior Assistant Resident, Department of General Surgery, Duke University Medical Center, Durham, N.C.
1999-2000 Chief Resident, Department of General Surgery, Duke University Medical Center, Durham, N.C.
2000-2 Cardiothoracic Surgery Resident, Division of Thoracic Surgery, Duke University Medical Center, Durham, N.C.
Honors and Awards:
1994 First Place, National Board of Surgery, In-Service Examination, Duke University Medical Center.
1995-7 NIH National Research Service Award IF32HL09303, “Cardiac Mechanics in Pressure-Overload Heart Failure.”
1998 Pilling Weck Award for Excellence in Clinical and Traditional Science, “Myocardial Gene Transfer Enhances Function of the Transplanted Heart.”
2004 American College of Cardiology Foundation/Pfizer Visiting Professorship in Cardiovascular Medicine for R.C.J. Chiu, MD, PhD, “Myocardial Stem Cell Transplantation”
Liscensure:
1994 Diplomate, National Board of Medical Examiners
1997 North Carolina Medical License
2001 Diplomate, American Board of Surgery
2003 Diplomate, American Board of Thoracic Surgery
Societies: 2000-Present Member, Sabiston Surgical Society
2002-Present Member, North Carolina Medical Society
2003-Present Member, Association for Academic Surgery
2004-Present Member, Southern Thoracic Surgical Association
2004-Present Fellow, American College of Chest Physicians
2004-Present Member, Society of Thoracic Surgeons
2004-Present Fellow, American College of Surgeons
2004-Present Fellow, American College of Cardiology
Languages: Czech (fluent), French, Spanish
Abstracts: 1. Nahas, G., Trouve, R., Manger, W., Kypson, A. Cocaine, catecholamines and calcium homeostasis, The Physiologist 32:172, 1989.
2. Trouve, R., Nahas, G., Kypson, A. Angiotensin II and cocaine lethal intoxication. FASEB Journal Volume 3, No.3, Part I, 1989.
3. Trouve, R., Kypson, A., Latour C., Nahas, G. Cocaine blunts the baroreceptor reflex in rats. European Journal of Clinical Pharmacology Volume 36, Sup I, 1989.
4. Trouve, R., Kypson, A., Sitbon, M., Latour, C., Nahas, G. Intoxication grave par amphetamine: une nouvelle approche. Journal of Toxicology and Clinical Experimentation Volume 9(3), p210. 1989.
5. Trouve, R., Nahas, G., Manger, W., Kypson, A. Anticatecholaminergic properties of cocaine antidotes. FASEB Journal Volume 4, No.4, Part II, 1990.
6. Kypson, A.P., El-Shewy, H.M., Soloma, S.H., Abd-Alla, O., Lowe, J.E., Abdel-aleem, S. Effects of chronic inhibition of fatty acid oxidation on stress tolerance in the heart. Journal of Molecular and Cellular Cardiology Volume 29, No.6, p. A192. 1997.
7. Channon, K.M., Kypson, A.P., Blazing, M.A., Daggett C.W., Koch, W.J., George, S.F. In vivo pulmonary artery adenoviral gene transfer of nitric oxide synthase enhances pulmonary nitric oxide production. Heart Volume 77, Supp. I, p. P8. 1997.
8. Maurice, J.P., Kypson, A.P., Skaer, C.A., Koch, W.J. -adrenergic signaling characteristics in an infarct heart model. Circulation Volume 96, No.8, p. I-362. 1997.
9. Skaer, C.A., Akhter, S.A., Kypson, A.P., McDonald, P., Peppel, K.C., Koch, W.J. Adenoviral-mediated -adrenergic rescue of failing ventricular cardiomyocytes. Circulation Volume 96, No.8, p. I-483. 1997.
10. Kypson, A.P., Akhter, S.A., Peppel, K., Hendrickson, S.C., McDonald, P., Lilly, R.E., Glower, D.D., Lefkowitz, R.J., Koch, W.J. Adenoviral-mediated gene transfer of the 2-adrenergic receptor improves function of the transplanted rat heart. Circulation Volume 96, No.8, p. I-670. 1997.
11. Channon, K.M., Kypson, A.P., Daggett, C.W., Blazing, M.A., Koch, W.J., George, S.F. Enhanced pulmonary nitric oxide production and vasomotor function after in vivo pulmonary artery adenoviral gene transfer of nitric oxide synthase. European Heart Journal Volume 18, Supp.3, p.118. 1997.
12. St.Louis, J.D., Hendrickson, S.C., Kypson, A.P., Hughes, G.C., Coleman, R.E., Donavan, C.L., Degrado, T.R., Seabage, L., Abdel-aleem, S., Landolfo, K.P., Lowe, J.E. An experimental model of myocardial hibernation. Journal of American College of Cardiology Volume 31, No.2, p.409A. 1998.
13. Shah, A.S., Atkins, B.Z., Hata, J.A., Kypson, A.P., Walton, G.B., Sudarshen, S., Davis, J.W., Wolfe, W.G., Glower, D.D. Right ventricular overload depresses ventricular performance and alters global beta-adrenergic signaling. Circulation Volume 98, No.17, p. I-554-5. 1998.
14. Hughes, G.C., Annex, B.H., Yin, B., Pippen, A.M., Lin, P., Kypson, A.P., Peters, K.G., Lowe, J.E., Landolfo, K.P. Transmyocardial laser revascularization (TMR) limits in vivo adenoviral-mediated gene transfer in porcine myocardium. Journal of American College of Cardiology Volume 33, No.2, Supp.A, p.355A. 1999.
15. Tai, O.S., Shah, A.S., Kypson, A.P., Glower, D.D., Koch, W.J. Brain death induces increased -adrenergic receptor (AR) kinase 1 expression in the heart. Circulation Volume 100, No.18, p. I-165. 1999.
16. Hughes, G.C., Baklanov, D.V., Annex, B.H., Biswas, S.S., Kypson, A.P., Pippen, A.M., Yin, B., Donovan, C.L., Lowe, J.E., Landolfo, K.P. Denervation is not the long-term mechanism of action of transmyocardial laser revascularization. Circulation Volume 100, No.18, p. I-249. 1999.
17. Shah, A.S., White, D.C., Baklanov, D., Lilly, R.E., Kypson, A.P., Glower, D.D., Koch, W.J. In vivo intracoronary delivery and overexpression of a ARK inhibitor to the failing heart: prospects for molecular ventricular assistance. Circulation Volume 100, No.18, p. I-481. 1999.
18. Shah, A.S., Lilly, R.E., Kypson, A.P., Tai, O.S., Hata, J.A., Glower, D.D., Koch, W.J. In vivo intracoronary delivery to and overexpression of the human β2-adrenergic receptor (β2-AR) in the left ventricle. American Heart Association Scientific Conference on Molecular, Cellular, and Integrated Physiological Approaches to the Failing Heart. 1999.
19. Glower, D.D., Kypson, A.P. Port-access aortic and mitral valve replacement. Cardiothoracic Techniques and Technologies Volume 7, p.74. 2001.
20. Bolotin, G., Kypson, A.P., Nifong L.W., Chitwood Jr., W.R. Video-assisted mitral valve repair and left atrial ablation through a right mini-thoracotomy. Heart Surgery Forum Volume 6, No.2, p.105. 2003.
21. Kypson, A.P. Perfusion for robotic and minimally invasive cardiac surgery. Heart Surgery Forum Volume 6, No.2, p.111-2. 2003.
22. Bolotin, G., Scott, W.W., Austin, T.C., Charland, P.J., Kypson, A.P., Nifong, L.W., Reade, C.C., Chitwood Jr., W.R. Robotic skeletonizing of the mammary artery: is it safe? Heart Surgery Forum Volume 6, Supp.1, p. S39-40. 2003.
23. Bolotin, G., Shapira Y., Gotler Y., Frolkis I.V., Kypson, A.P., Nesher N., Chitwood Jr., W.R., Uretzky G. The potential advantage of “no-touch” aortic technique in off-pump complete arterial revascularization. Heart Surgery Forum Volume 6, Supp.1, p. S51. 2003.
24. Bolotin, G., Kypson, A.P., Chu, V., Nifong, W.L., Chitwood Jr., RW. Should a video-assisted mini-thoracotomy be the approach of choice for re-operative mitral valve surgery? Society for Heart Valve Disease 2003.
25. Reade, C.C., Bower, C.E., Schuler, C.M., Austin, T.C., Charland, P.J., Sun, Y.S., Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Acute effects of suction retraction on atrial hemodynamics and histology. Journal of the American College of Surgeons Volume 197, No.3 (Supplement), p. S26. 2003.
26. Bolotin, G., Kypson, A.P., Nifong, L.W., Reade, C., Freund, Jr., W., Chitwood, Jr., W.R. Robotic-assisted mitral valve repair with microwave atrial fibrillation ablations: early clinical results. Journal of the American College of Surgeons Volume 197, No.3 (Supplement), p. S24. 2003.
27. Koutlas, T.C., Maziarz, D.M., Conquest, A.M., Williams, J.M., Scott, W.W., Kypson, A.P., Chitwood Jr., W.R. Clinical results using the St. Jude medical “symmetry” aortic connector system in 400 coronary artery bypass patients. Journal of American College of Cardiology Volume 43, No. 5, Supplement A, p. 273A. 2004.
28. Reade, C.C., Bower, C.E., Bailey, B.M., Maziarz, D.M., Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Learning curves associated with robotic mitral valve repair. Heart Surgery Forum Volume 7, No.4, p. E302. 2004.
29. Kypson, A.P. Perfusion for minimally invasive cardiac surgery. Heart Surgery Forum Volume 7, No.4, p. E298-9. 2004.
30. Kypson, AP, Bolotin, G, Reade, CC, Bailey, BM, Nifong, LW, Holbert, D, Chitwood, RW. Potential benefits of a minimally invasive approach versus median sternotomy in patients undergoing mitral valve surgery.
31. Kypson, AP, Reade, CC, Scott, WW, Williams, JM, Koutlas, TC. Intermediate results of the St. Jude Medical Symmetry™ proximal saphenous vein graft connector.
32. Cook, RC, Nifong, LW, Charland, P, Enterkin, J, Kypson, AP, Reade CC, Chitwood, WR. Significant reduction in annuloplasty time with the use of nitinol clips in robotically-assisted mitral valve repair.
33. Cook, R.C., Nifong, L.W., Lashley, G.G., Duncan, R.A., Campbell, J.A., Law, Y.B., Kypson, A.P., Chitwood Jr., W.R. Early experience with echocardiographically-guided selection of annuloplasty band in robotically-assisted mitral valve repair. New Era 2005.
34. Cook, R.C., Nifong, L.W., Kypson, A.P., Reade, C.C., Law, Y.B., Chitwood Jr., W.R. Bileaflet mitral repairs using robotic assistance in patients with Barlow’s valves. New Era 2005.
Manuscripts: 1. Kypson, A.P., Akhter, S.A., Peppel, K., Lilly, R.E., Dolber, P., Glower, D.D., Lefkowitz, R.J., Koch, W.J. Global overexpression of -adrenergic receptors in the myocardium via adenoviral-mediated gene transfer. Surgical Forum Volume XLVII, p.282-4. 1996.
2. Lilly, R.E., Peppel, K., Kypson, A.P., Silvestry, S.C., Glower, D.D., Koch, W.J., Lefkowitz, R.J. Intracoronary administration of adenovirus for gene transfer into adult rabbit myocardium. Surgical Forum Volume XLVII, p.279-281. 1996.
3. Sabiston Jr., D.C., Kypson, A.P., Friesinger, G.C. Severe stenosis of the left main coronary artery with endarterectomy and graft:33-year follow-up. Annals of Thoracic Surgery Volume 64, No.5, p.1559-60. 1997.
4. Kypson, A.P., Daggett, C.W., Channon, K.M., Gullotto, C., George, S.E., Koch, W.J. In vivo pulmonary adenoviral-mediated gene transfer of nitric oxide synthase increases nitric oxide production. Surgical Forum Volume XLVIII, p.333-5. 1997.
5. Kypson, A.P., Akhter, S.A., Skaer, C.A., McDonald, P.H., Peppel, K.C., Glower, D.D., Lefkowitz, R.J., Koch, W.J. Restoration of -adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer. Proceedings of the National Academy of Sciences, USA. Volume 94, p.12100-5. 1997.
6. Kypson, A.P., Peppel, K., Akhter, S.A ., Lilly, R.E., Glower, D.D., Lefkowitz, R.J., Koch, W.J. Ex vivo adenoviral-mediated gene transfer in the transplanted adult rat heart. Journal of Thoracic and Cardiovascular Surgery Volume 115, No.3, p.623-30. 1998.
7. Shah, A.S., Hata, J.A., Kypson, A.P., Glower, D.D., Koch, W.J. Adenoviral-mediated overexpression of the beta-adrenergic receptor kinase inhibitor in a cardiac transplant model. Surgical Forum Volume XLIX, p.278-9. 1998.
8. Hughes, G.C., Lowe, J.E., Kypson, A.P., St.Louis, J.D., Pippen, A.M., Peters, K.G., Coleman, R.E., DeGrado, T.R., Donovan, C.L., Annex, B.H., Landolfo, K.P. Neovascularization after transmyocardial laser revascularization in a model of chronic ischemia. Annals of Thoracic Surgery Volume 66, No.6, p.2029-36. 1998.
9. Maurice, J.P, Shah, A., Kypson, A.P., Hata, J., White, D.C, Glower, D.D., Koch, W.J. Molecular -adrenergic signaling abnormalities in failing rabbit hearts after infarction. American Journal of Physiology Volume 276, Issue 6, p. H1853-60. 1999.
10. Hughes, G.C., Kypson, A.P., St.Louis, J.D., Annex, B.H., Coleman, R.E., DeGrado, T.R., Donovan, C.L., Lowe, J.E., Landolfo, K.P. Improved perfusion and contractile reserve after transmyocardial laser revascularization in a model of hibernating myocardium. Annals of Thoracic Surgery Volume 67, No.6, p.1714-20. 1999.
11. Kypson, A.P., Hendrickson, S.C., Akhter, S.A., Wilson, K., McDonald, P.H., Lilly, R.E., Dolber, P.C., Glower, D.D., Lefkowitz, R.J., Koch, W.J. Adenoviral-mediated gene transfer of the 2 -adrenergic receptor enhances cardiac function. Gene Therapy Volume 6, No.7, p.1298-1304. 1999.
12. Hughes, G.C., Annex, B.H., Yin, B., Pippen, A.M., Lin, P., Kypson, A.P., Peters, K.G., Lowe, J.E., Landolfo, K.P. Transmyocardial laser revascularization (TMR) limits in vivo adenoviral-mediated gene transfer in porcine myocardium. Cardiovascular Research Volume 44, No. 1, p. 81-90. 1999.
13. Shah, A.S., Lilly, R.E., Kypson, A.P., Tai, O., Hata, J.A., Baklanov, D., Glower, D.D., Koch, W.J. In vivo intracoronary delivery to and overexpression of the human 2-adrenergic receptor in the right ventricle: prospects for molecular right ventricular assistance. Surgical Forum Volume L, p.119-20. 1999.
14. Hughes, G.C., Kypson, A.P., Yin, B., St.Louis, J.D., Biswass, S.S., Annex, B.H., Coleman, R.E., DeGrado, T.R., Donovan, C.L., Landolfo, K.P., Lowe, J.E. Induction of angiogenesis following transmyocardial laser revascularization in a model of chronic ischemia: a comparison of holmium:YAG, carbon dioxide, and excimer lasers. Surgical Forum Volume L, p.115-7. 1999.
15. Shah, A.S., Lilly, R.E., Kypson, A.P., Tai, O., Hata, J.A., Pippen, A., Silvestry, S.C., Lefkowitz, R.J., Glower, D.D., Koch, W.J. Intracoronary delivery and overexpression of the 2-adrenergic receptor in the heart: prospects for molecular VAD. Circulation Volume 101, No.4, p.408-14. 2000.
16. St. Louis, J.D., Hughes, G.C., Kypson, A.P., DeGrado, T.R., Donovan, C.L., Coleman, R.E., Yin, B., Steenbergen, C., Landolfo, K.P., Lowe, J.E. An experimental model of chronic myocardial hibernation. Annals of Thoracic Surgery Volume 69, No.5, p.1351-57. 2000.
17. Shah, A.S., Atkins, B.Z., Hata, J.A., Tai, O., Kypson, A.P., Lilly, R.E., Davis, J.W., Koch, W.J., Glower, D.D. Early effects of right ventricular volume overload on ventricular performance and beta-adrenergic signaling. Journal of Thoracic and Cardiovascular Surgery Volume 120, No.2, p.342-9. 2000.
18. Hughes, G.C., Kypson, A.P., Annex, B.H., Yin, B., St. Louis, J.D., Biswas, S.S., Coleman, E., DeGrado, T.R., Donovan, C.L., Landolfo, K.P., Lowe, J.E. Induction of angiogenesis after TMR: a comparison of holmium:YAG, CO2, and excimer lasers. Annals of Thoracic Surgery Volume 70, No.2, p.504-9. 2000.
19. Shah, A.S., White, D.C., Tai, O., Hata, J.A., Wilson, K.H., Pippen, A., Kypson, A.P., Glower, D.D., Lefkowitz, R.J., Koch, W.J. Adenovirus-mediated genetic manipulation of the myocardial -adrenergic signaling system in transplanted hearts. Journal of Thoracic and Cardiovascular Surgery Volume 120, No.3, p.581-8. 2000.
20. Kypson, A.P., Wentzensen, N., Georgiade, G.S., Vaslef, S.N. Traumatic vertebrojugular arteriovenous fistula: a case report. Journal of Trauma Volume 49, No.6, p.1141-3. 2000.
21. Shah, A.S., White, D.C., Emani, S., Kypson, A.P., Lilly, R.E., Wilson, K., Glower, D.D., Lefkowitz, R.J., Koch, W.J. In vivo ventricular gene delivery of a -adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction. Circulation Volume 103, No.9, p.1311-6. 2001.
22. Glower, D.D., Landolfo, K.P., Kypson, A.P., Bashore, T.M., Harrison, K., Wang, A., Warner, J.J. Is port-access applicable to complex mitral valve repair? Heart Surgery Forum Volume 5, Supp.1, p. S76-87. 2002.
23. Kypson, A.P., Glower, D.D. Port-access approach for combined aortic and mitral valve surgery. Annals of Thoracic Surgery Volume 73, No.5, p. 1657-8. 2002.
24. Kypson, A.P., Glower, D.D. Minimally invasive tricuspid surgery using port-access. Annals of Thoracic Surgery Volume 74, No.1, p. 43-5. 2002.
25. Kypson, A.P., Onaitis, M.W., Feldman, J.M., Tyler, D.S. Carcinoid and chylous ascites: an unusual association. Journal of Gastrointestinal Surgery Volume 6, No.5, p. 781-3. 2002.
26. Kypson, A.P., Warner, J.J., Telen, M.J., Milano, C.A. Paroxysmal cold hemoglobinuria and cardiopulmonary bypass: a case report. Annals of Thoracic Surgery Volume 75, No.2, p. 579-81. 2003.
27. Kypson, A.P., Morphew, E., Jones, R., Gottfried, M.R., Seigler, H.F. Heterotopic ossification in rectal cancer: a rare finding with a novel proposed mechanism. Journal of Surgical Oncology Volume 82, No.2, p. 132-6. 2003.
28. Swaminathan, M., Kypson, A.P., Perna, J.G., Davis, R.D., Stafford-Smith, M. Right ventricular rupture during off pump coronary bypass surgery. Journal of Cardiothoracic and Vascular Anesthesiology Volume 17, No.1, p. 87-9. 2003.
29. Chitwood Jr., W.R., Kypson, A.P., Nifong, L.W. Robotic mitral valve surgery: a technologic and economic revolution for heart centers. American Heart Hospital Journal Volume 1, No.1, p.30-9. 2003.
30. Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Robotic mitral valve surgery. Seminars in Thoracic and Cardiovascular Surgery Volume 15, No.2, p. 121-9. 2003.
31. Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Robotic mitral valve surgery. Surgical Clinics of North America Volume 83, No.6, p. 1387-1403. 2003.
32. Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Robotic cardiac surgery. Journal of Long-Term Effects of Medical Implants Volume 13, No.6, p. 451-64. 2003.
33. Bolotin, G., Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. A technique for evaluating competitive flow for intra-operative decision making in coronary artery surgery. Annals of Thoracic Surgery Volume 76, No.6, p.2118-20. 2003.
34. Bolotin, G., Kypson, A.P., Reade, C.C., Chu, V., Freund, W.L., Nifong, W.L., Chitwood Jr., RW. Should a video-assisted mini-thoracotomy be the approach of choice for re-operative mitral valve surgery? The Journal of Heart Valve Disease Volume 13, p.155-8. 2004.
35. Bolotin, G., Scott, W.W., Austin, T.C., Charland, P.J., Kypson, A.P., Nifong, L.W., Salleng, K., Chitwood Jr., W.R. Robotic skeletonizing of the internal thoracic artery: is it safe? Annals of Thoracic Surgery Volume 77, No.4, p.1262-5. 2004.
36. Kypson, A.P., Felger, J.E., Nifong, L.W., Chitwood Jr., W.R. Robotics in valvular surgery: 2003 and beyond. Current Opinion in Cardiology Volume 19, No.2, p. 128-33. 2004.
37. Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Robot-assisted surgery: training and re-training surgeons. International Journal of Medical Robotics and Computer Assisted Surgery Volume 1, No.1, p. 70-6. 2004.
38. Kypson, A.P., Chitwood Jr., W.R. Robotic applications in cardiac surgery. International Journal of Advanced Robotic Systems Volume 1, No 2, p. 87-92. 2004.
39. Kypson, A.P., Chitwood Jr., W.R. Robotic mitral valve surgery. American Journal of Surgery Volume 188, No. 4S1, p. 83-8. 2004.
40. DeRose Jr., J.J., Kypson, A.P. Robotic arrhythmia surgery and resynchronization. American Journal of Surgery Volume 188, No. 4S1, p. 104-11. 2004.
41. Bolotin, G., Kypson, A.P., Nifong, L.W., Chitwood Jr., R.W. Robotically-assisted left atrial fibrillation ablation and mitral valve repair through a right mini-thoracotomy. Annals of Thoracic Surgery Volume 78, No. 4, p.e63-4. 2004.
42. Khan, N.U., Lerrick, K.S., Kypson, A.P., Saha, P.K. Pitfalls of coronary angiography in aortic dissection. International Journal of Angiology Volume 13, p. 84-5. 2004.
43. Reade, C.C., Johnson, J.O., Bolotin, G., Freund Jr., W.L., Jenkins, N.L., Bower, C.E., Masroor, S., Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Combining robotic mitral valve repair and microwave atrial fibrillation ablation: techniques and initial results. Annals of Thoracic Surgery Volume 79, p.480-4. 2005.
44. Kypson, A.P., Chitwood Jr., W.R. The use of robotics in cardiovascular surgery. Future Cardiology Volume 1, No.1, p.61-7. 2005.
45. Reade, C.C., Bower, C.E., Bailey, B.M., Maziarz, D.M., Masroor, S., Kypson, A.P., Nifong, L.W., Chitwood Jr, W.R. Robotic mitral valve annuloplasty with double arm nitinol U-clips. Annals of Thoracic Surgery (in press).
46. Kypson, A.P., Chitwood Jr., W.R. Palmar microcirculation following harvesting of the radial artery in coronary revascularization (Invited Commentary). Annals of Thoracic Surgery (in press).
47. Kypson, A.P., Chitwood Jr., W.R. Early clinical results with a magnetic connector for distal coronary artery anastomoses (Invited Commentary). Annals of Thoracic Surgery (in press).
48. Kypson, A.P., Frazier, D.W., Moran, J.F. Internal mammary artery injury following transvenous pacemaker implantation. Journal of Thoracic and Cardiovascular Surgery (in press).
49. Reade, C.C., Bower, C.E., Schuler, C.M., Austin, T.C., Charland, P.J., Smith, N.L., Sun, Y.S., Nifong, L.W., Chitwood Jr., W.R., Kypson, A.P. Acute effects of suction retraction on atrial hemodynamics and histology. Journal Thoracic and Cardiovascular Surgery (in press).
50. Reade, C.C., Bower, C.E., Kypson, A.P., Wooden, W.A., Chitwood Jr., W.R. Re-examining contraindications for minimally invasive mitral valve surgery. Heart Surgery Forum (in press).
51. Kypson, A.P., Chitwood Jr., W.R. Robotically assisted cardiac surgery. Indian Heart Journal (in press).
52. Reade CC, Kypson AP, Williams JM. Valve sparing aortic root replacement after prior Starr-Edwards aortic valve replacement. Annals of Thoracic Surgery (submitted).
53. Reade C.C., Kypson, A.P., Chitwood, W.R. 8th Annual NewEra cardiac care: innovation and technology. Future Cardiology (in press).
54. Kypson, AP. Sudden cardiac arrest after coronary bypass grafting secondary to massive carbon dioxide embolism. Journal of Thoracic and Cardiovascular Surgery (submitted).
Videos: 1. Kypson, A.P., Glower, D.D. Redo tricuspid operation using port access. American College of Surgeons. 2001.
2. Kypson, A.P., Glower, D.D. Tricuspid repair using port access. Southern Thoracic Surgical Association. 2001.
3. Chitwood, W.R., Nifong, L.W., Kypson, A.P., Bolotin, G., Bower, C.E., Fuller, J.D. Robotic mitral valve repair. American College of Surgeons. 2002.
4. Bolotin, G., Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Video-assisted mitral valve repair and left atrial ablation through a right mini-thoracotomy. New Era Cardiac Care. 2003.
6. Reade, C.C., Bowyer, C.E., Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Combining robotic mitral valve repair and microwave atrial fibrillation ablation. Southern Thoracic Surgical Association. 2003.
7. Reade, C.C., Bowyer, C.E., Bailey, B.M., Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Robotic mitral valve annuloplasty utilizing double arm nitinol u-clips. Southern Thoracic Surgical Association. 2003.
8. Reade, C.C., Kypson, A.P., Cook, R.C., Nifong, L.W., Chitwood Jr., W.R. Complex robotic mitral valve repair: the Barlow’s valve. New Era Cardiac Care. 2005.
Book Chapters: 1. Kypson, A.P., Ludwig, K. Laparoscopic Colectomy and Abdominoperineal Resection. In Atlas of Laparoscopic Surgery, 2nd edition, Philadelphia, Appleton & Lange. pp. 12.1-12.13. 1999.
2. Kypson, A.P. Cardiopulmonary Resuscitation. In Surgical Intensive Care Handbook of Duke University, 5th edition, St. Louis, Mosby. pp. 39-57. 2000.
3. Kypson, A.P., Chitwood Jr., W.R. Cardiopulmonary Bypass during Port-Access™ and Robotic Surgery. In Techniques in Extracorporeal Circulation, 4th edition, London, Arnold. pp. 298-314. 2004.
4. Kypson, A.P., Nifong L.W., Chitwood Jr., W.R. Telerobotic-assisted cardiac valve surgery in Primer of Robotic and Telerobotic Surgery, 1rst edition, Philadelphia, Lippincott Williams & Wilkins. pp. 118-123. 2004.
5. Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Robotic and novel visualization systems in Sabiston & Spencer’s Surgery of the Chest, 7th edition, Philadelphia, Elsevier Saunders. pp. 1385-1396. 2005.
6. Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Minimally invasive cardiac surgery in Mastery of Endoscopic and Laparoscopic Surgery, 2nd edition, Philadelphia, Lippincott Williams & Wilkins. pp. 559-67. 2005.
7. Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Mitral valve repair- robotic minimally invasive in Mastery of Cardiothoracic Surgery, 2nd edition, (in press).
Clinical Investigations/Grants: 1. Co-PI, Corgentech PREVENT IV Study (CGTOO3-04), “A phase III, multi-center randomized, double-blind, placebo-controlled trial of the ex vivo treatment with CGTOO3 of coronary vein grafts in patients undergoing coronary artery bypass graft procedures.” 2002.
2. PI, HEMASEEL APR Study (BPL 100), “A phase III two-part, randomized, comparative, multicenter study of HEMASEEL APR manufactured at BPL to a control agent and to HEMASEEL APR manufactured at Immuno AG.” 2003.
3. PI, TELFA AMD Island dressing, “Effects pm wound healing and incidence of sternal wound infections in subjects who have undergone cardiac surgical procedures requiring median sternotomy.” 2004.
4. PI, PRIMO-CABG II (#2003141), “A multicenter, randomized, double-blind, parallel-group, placebo-controlled study of 2 mg/kg bolus plus 24-hour 0.05 mg/kg/hr infusion of pexelizumab in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass.” 2004.
5. PI, FREEDOM trial, “Future revascularization evaluation in patients with diabetes mellitus: optimal management of multivessel disease.” 2004. (submitted).
6. Co-PI, “Role of atrial GIRK channels in the altered cardiac autonomic function associated with cigarette smoking.” Philip Morris External Research Program. $672,571. 2004. (submitted)
Editorial Boards: 1. Minimally Invasive Surgery Center, CTS Net
Reviewer: 1. American Heart Journal
2. Asian Cardiovascular and Thoracic Annals
3. Current Surgery
4. American College of Cardiology, Abstract Grader 2004
Presentations:
1. 82nd Clinical Congress of the American College of Surgeons, San Francisco, CA, October 9, 1996.
2. 77th Annual Meeting of the American Association for Thoracic Surgery, Washington, D.C., May 7, 1997.
3. 83rd Clinical Congress of the American College of Surgeons, Chicago, IL, October 15, 1997.
4. 70th Scientific Sessions of the American Heart Association, Orlando, FL, November 12 , 1997.
5. 87th Clinical Congress of the American College of Surgeons, New Orleans, LA, October 8, 2001.
6. 48th Annual Meeting of the Southern Thoracic Surgical Association, San Antonio, TX, November 7, 2001.
7. 6th Annual NewEra Cardiac Care, “Perfusion for Robotic and Minimally Invasive Cardiac Surgery” Dana Point, CA, January 3, 2003.
8. “Remote Access Perfusion Techniques for Minimally Invasive Cardiac Surgery” San Diego, CA, January 30-1, 2003.
9. 7th Annual NewEra Cardiac Care, “Perfusion for Minimally Invasive Cardiac Surgery” Dana Point, CA, January 10, 2004.
10. 53rd Annual Scientific Session, American College of Cardiology, “Robotic Valvular Surgery” New Orleans, LA, March 9, 2004.
11. 2nd Congress of the Polish Society of Cardiothoracic Surgeons, “Minimally Invasive Surgery of the Mitral Valve” Katowice, Poland, May 13, 2004.
12. Carolina Valve Symposium, “Percutaneous Valve Technology” Greenville, NC, September 28, 2004.
Moderator: 1. Abstract Session, 6th Annual NewEra Cardiac Care Meeting, Dana Point, CA. 2003.
2. Perfusion Mini-Symposium, 7th Annual NewEra Cardiac Care Meeting, Dana Point, CA. 2004.
3. Video Session, 7th Annual NewEra Cardiac Care Meeting, Dana Point, CA. 2004.
4. Meet the Experts, 53rd Annual Scientific Session, American College of Cardiology, “Robotic Valvular Surgery” New Orleans, LA. 2004.
5. Carolina Valve Symposium, Greenville, NC. 2004.
Internet Publications: 1. Smith, P., Kypson, A.P. Rate-control versus conversion strategy in postoperative atrial fibrillation: a prospective, randomized pilot study. Review in CT Digest.Com Volume 3, No.4. p. 5.
http://ctdigest.com/Apr01/Apr01.asp?rev=5 2. Reade, C.C., Bowyer, C.E., Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Combining robotic mitral valve repair and microwave atrial fibrillation ablation. CTSnet (Motion Picture)
http://www.ctsnet.org/realmedia/vidgal/vg2004_reade_robotic.ram 3. Reade, C.C., Bower, C.E., Bailey, B.M., Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Robotic Mitral Valve Annuloplasty Utilizing Double Arm Nitinol U-Clips. CTSnet (Motion Picture) rtsp://pune.medbiq.com/c1/STSA/Reade_MVR_2003.rm
4. Kypson, A.P., Nifong, L.W., Chitwood Jr., W.R. Robot-assisted surgery: training and re-training surgeons. International Journal of Medical Robotics and Computer Assisted Surgery.
http://www.roboticpublications.com/index.php?page=abstract0101&id=7&nav=nav1 5. Kypson, A.P. Minimally invasive cardiopulmonary bypass- oxymoron or not? CTSnet.
http://www.ctsnet.org/doc/9268 6. Kypson, A.P. Clinical experience with the mini-extracorporeal circulation system: an evolution or revolution? CTSnet.
http://www.ctsnet.org/doc/9468 7. Kypson, A.P. Endoscopic conduit harvesting. CTSnet.
8. Kypson, A.P. Cardiac surgery “mini” revolution. CTSnet.
http://www.ctsnet.org/sections/innovation/minimallyinvasive/articles/article-24.html
