Division of Health SciencesThe Harriet and John Wooten Laboratory

Health Sciences Campus

In The News

Research Efforts

 In April of 2014, the Wooten Laboratory received a research grant of $50,000 from Alzheimer's North Carolina, Inc with the title "A Multidisciplinary Approach to Fight Senior Dementia II: study of accelerated Alzheimer's mouse model and developmental toxicity".

In October of 2013, the Wooten Laboratory received a $50,100 donation from the Wooten family to further translational research and promote Wooten Laboratory research efforts.

In July of 2013, Dr. Qun Lu presented at Alzheimer Association International Conference in Boston, with the poster title "Small molecules targeting Rho GTPase signaling altered in Alzheimer's disease".

In June of 2013, the Wooten Laboratory received a research grant of $50,000 from Alzheimer's North Carolina, Inc. A press release on the grant title "A Multidisciplinary Approach to Fight Senior Dementia I: study physical exercise and cortical training on Alzheimer-like pathogenesis in mice." can be found at www.ecu.edu/dhs/newsStory.cfm?id=2798.

In May of 2013, Drs. Sonja Bareiss and Kori Brewer published a paper in Neuroscience Letter, titled "Excitotoxic spinal cord injury induced dysesthesias are associated with enhanced intrinsic growth of sensory neurons".

In February of 2013, the Wooten Laboratory presented to Eli Lily representatives for partnership discussion on neurodegenerative diseases research.

In January of 2013, Dr. Qun Lu published a paper in PNAS entitled "Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility". A press release on its relevance to Alzheimer's disease can be found at www.ecu.edu/dhs/newsStory.cfm?id=2631.

In November of 2012, the Wooten Laboratory sponsored Dr. Weiming Xia from VA Hospital in Boston, to deliver a talk in the14th annual Neuroscience Symposium and The Wooten Roundtable Discussion.

In November of 2012, the Wooten Laboratory sponsored Dr. Oscar Lopez, Director of University of Pittsburg Alzheimer's Disease Research Center, as the Wooten Lecturer in the 14th annual Neuroscience Symposium.

In May of 2012, Dr. Qun Lu received a grant from National Cancer Institute to study Rho GTPase as neuroprotection target in chemotherapy-induced neurodegeneration.

In September of 2011, the Wooten Laboratory received a $100,000 donation from the Wooten family to accelerate translational research and promote Wooten Laboratory research efforts.

In November of 2011, the Wooten Laboratory sponsored ECU Wooten Laboratory member Dr. Mark Mannie as the Wooten Lecturer in the 13th annual Neuroscience Symposium.

In September of 2011, Dr. Qun Lu, with the assistance and support of ECU Department of marketing professor Dr. Margy Conchar, has produced the Wooten Visibility. It was distributed on Sept. 17, 2011 at the Raleigh Alzheimer's Walk, Oct. 15, 2011 at the Washington Walk, and Nov. 12, 2011 at the Greenville Walk.

In July and September of 2011, Dr. Mark Mannie received two grants from National Institute of Neurological Disorders and Stroke to study therapeutic vaccines (TTV) in murine experimental autoimmune encephalomyelitis (EAE).

In May of 2011, Dr. Qun Lu received funding from PharmaTrophix for Alzheimer's disease drug applications in peripheral neurodegenerations.

In February of 2011, the funding of six Wooten projects was announced to investigate the molecular and cellular mechanisms of Alzheimer's disease-like pathogenesis in transgenic mice.

In February of 2011, the Wooten Laboratory received a $100,000 donation to accelerate translational research and promote Wooten Laboratory research efforts.

In November of 2010, the Wooten Laboratory co-sponsored the 12th annual East Carolina Neuroscience Symposium and the Wooten Lecture by Dr. Sandra Kelly of University of South Carolina.

In October of 2010, Dr. Qun Lu published a paper in Journal of Alzheimer's Disease entitled "Alzheimer's disease-linked presenilin mutation (PS1M146L) induces filamin expression and gamma-secretase independent redistribution".

In September of 2010, Dr. Alex Murashov received a grant from National Institute for Environmental Health Sciences to study microRNA pathway in mechanisms of nanoparticles neurotoxicity.

In February of 2010, the funding of six Wooten projects was announced to investigate the molecular and cellular mechanisms of Alzheimer's disease and other neurological disorders.

In October of 2009, The Wooten Laboratory sponsored Dr. Donald Price, MD, Director of Johns Hopkins University Alzheimer's Disease Center and Dr. Dwight German of University Texas Southwestern m Medical Center to deliver the Wooten Lectures on Alzheimer's disease research at 11th Annual Neuroscience Symposium.

In October of 2008, The Wooten Laboratory sponsored Dr. Michael Irizarry, MD, MPH from GlaxoSmithKline, and Epidemiology Division for the talk titled "Biomarkers and Imaging Markers in Alzheimer's Disease" at 10th Annual Neuroscience Symposium.

The Wooten Laboratory is a co-sponsor of the Annual Symposia of East Carolina Chapter of Society for Neuroscience (ECCSN) from 2008 to 2013. The annual meetings are held in November each year in Greenville, North Carolina. The Wooten Laboratory has supported the Wooten Lectures given by distinguished clinicians or scientists investigating Alzheimer's disease and/or other neurodegenerative diseases (view ECCSN website).The Wooten Laboratory has also funded and presented awards for Best Student Presentation at the symposia.


Community Awareness and Visibility

In September of 2014, Drs. Sonja Bareiss, Yan-Hua Chen, Jamie DeWitt, and Tuan Tran along with Dr. Qun Lu, participated in the education exhibits at Washington Alzheimer Walk. Dr. Bob Lust also joined in the Walk. The Walk (sponsored by AlzNC) raised $30,000 in this 10th annual Alzheimer's Walk in Washington. View photos of this event.

In November of 2013, Dr. Jamie DeWitt gave a presentation to a senior group at Vidant. It was titled "The nuts and bolts of Alzheimer's disease research at ECU".

In November of 2013, Dr. Tae Lee, Dr. Qun Lu and Dr. Robert Lust participated in the education exhibits at Greenville Alzheimer Walk. They also walked with thousands of supporters for ~1 miles.

In September of 2013, Dr. Jamie DeWitt gave a presentation to the Alzheimer's Professional Partnership meeting in Greenville. Its title was: "Alzheimer's disease and neurodegenerative disorders research at East Carolina University".

In November of 2012, Dr. Daniel Lee, Dr. Qun Lu, and Dr. Robert Lust participated in the education exhibits at Greenville Alzheimer Walk. They also walked with thousands of supporters for ~1 miles.

In October of 2012, Dr. Daniel Lee, Dr. Qun Lu, and Dr. Sonja Bareiss participated in the education exhibits at Washington Alzheimer Walk. Dr. Qun Lu, as well as Dr. Yan-hua Chen of ECU walked with hundreds of supporters for ~2 miles. The Walk has pledged for further support for research at the Wooten Laboratory.

In October of 2011, Dr. Daniel Lee, Dr. Qun Lu, and Dr. Sonja Bareiss participated in the education exhibits at Washington Alzheimer Walk. Dr. Jean Weng, a visiting clinical pharmacologist in Dr. Qun Lu's research group, also participated in the Walk. The Walk (sponsored by AlzNC) donated $5,000 to the Wooten Laboratory for research in Alzheimer's disease.

Wooten Laboratory donation - 2011

In October of 2010, Dr. Sonja Bareiss led the Wooten Laboratory and participated in the Washington Alzheimer Walk. The Walk (sponsored by AlzNC) donated $1,000 to the Wooten Laboratory for research in Alzheimer's disease.

Wooten Laboratory donation - 2010

In May and August of 2010, Dr. Irene Hamrick and Dr. Qun Lu continued to rally support for the Alzheimer's Walk (sponsored by www.gotricounty.com of Alzheimer's Foundation) to be held in Washington, North Carolina in October of 2010.

In May and June of 2010, Dr. Qun Lu participated in round table discussion about legal issues regarding the care of dementia patients and communication with their families.

In May of 2010, Dr. Qun Lu and Dr. Irene Hamrick visited Cypress Glen Memory Center. They toured the facility and discussed the care of dementia patients in eastern North Carolina with Laura Jett, Director of Memory Care unit.