The Department of Physiology houses internationally
recognized investigators whose research programs in basic and applied
biomedical sciences emphasize the study of cellular and molecular basis of tissue
function. The research programs are
focused on understanding the integrative mechanisms of physiological processes
within the context of both health and disease.
The investigators emphasize
an integrative approach to biomedical science, with expertise in research
methods for investigating cardiac function, pulmonary and vascular regulation,
metabolism and bioenergetics, stem cell differentiation, skeletal muscle
biology, spinal cord injury, nerve regeneration and circadian rhythms.
David Tulis was awarded an R15 from the NIH National Heart Lung and Blood
Institute to study “Acid-sensing GPCRs in vascular inflammation and growth”. The
broad goal of this research is to determine precise roles and mechanisms of
GPR4 and GPR68 in soliciting pathologic vascular endothelial cell inflammation
and adhesion and vascular smooth muscle growth. Anticipated findings promise to
shift our current understanding of vascular cell signaling and will provide new
avenues for basic and clinical investigation with the hopes of identifying
novel, more selective targets for therapeutic intervention in cardiovascular
A. Powers was awarded a research grant from the Sexual Medicine Society of
North America. Her grant was titled “Preservation of erectile function and
neuritogenesis using testosterone supplementation following androgen
deprivation and radical prostatectomy” and the award was for $5000. These findings will advance our understanding
of testosterone on cavernous nerve health and help optimize testosterone
treatment strategies following radical prostatectomy to restore sexual function
and quality of life to prostate cancer survivors. Shelby works in the lab of Dr. Johanna
Terence Ryan, Ph.D. was
awarded an NIH Ruth L. Kirschstein National Research Service Award (NRSA)
Individual Postdoctoral Fellowship (Parent F32). The award will support Terence
for in training for 3 years with a stipend and institutional allowance to
further his research in "Skeletal Muscle Mitochondria and Peripheral
Arterial Disease Pathology". Dr.
Ryan works in the lab of Dr. Joseph McClung.
Dr. Johanna Hannan delivers seminar on the impact
of neurovascular injury on sexual dysfunction in the Department of Physiology
at Augusta University (http://www.augusta.edu/mcg/phy/).
Dr. Espen Spangenburg gives invited seminar
on the role of BRCA1 in skeletal muscle at the University of Oregon in the
Department of Human Physiology (http://physiology.uoregon.edu/).