Department of Radiation Oncology
The Brody School of Medicine at East Carolina University
600 Moye Blvd.
Greenville, NC 27834
Phone (252) 744-2900 / Fax (252) 744-2812
M.D., University of Illinois-Urbana Champaign, 1995
Internship: Saint Rafael's Hospital, New Haven, CT., 1996
Radiation Oncology Residency: University of Maryland, 2000
Ph.D., Physics, Yale University, 1986
Board Certification
Board Certified Radiation Oncologist by the American Board of Radiology, 2000
Clinical Services
Head and neck malignancies
Genitourinary malignancies (including prostate and bladder cancer)
Brachytherapy including prostate seed implants
Image Guided Radiation Therapy (IGRT)
Intensity Modulated Radiation Therapy (IMRT)
Stereotactic radiosurgery and radiotherapy
Gamma Knife radiosurgery
Research Interests
Clinical and translational research in genitourinary and head and neck malignancies
Technology of radiation oncology and medical physics
Selected Publications
Russo S, Butler J, Ove R, Blackstock AW. Locally advanced pancreatic cancer: a review.Semin Oncol. 2007 Aug;34(4):327-34.
Ove R, Foote RL, and Bonner JA. Nasopharyngeal Carcinoma, in Clinical Radiation Oncology, Gunderson LL and Tepper JE ed., 2nd edition, 2006.
Ahmed RS, Shen S, Ove R, Duan J, Fiveash JB, Russo SM. Intensity modulation with respiratory gating for radiotherapy of the pleural space.Med Dosim. 2007 Spring;32(1):16-22.
Ye SJ, Ove R, Naqvi SA. Doppler broadening effect on low-energy photon dose calculations using MCNP5 and PENELOPE. Health Phys. 2006 Oct;91(4):361-6.
Ahmed RS, Ove R, Duan J, Popple R, Cobb GB. Intensity-modulated radiotherapy (IMRT) for carcinoma of the maxillary sinus: a comparison of IMRT planning systems.
Med Dosim. 2006 Fall;31(3):224-32.
Bonner JA, Harari PM, Giralt J, Azarnia N, Shin DM, Cohen RB, Jones CU, Sur R,
Raben D, Jassem J, Ove R, Kies MS, Baselga J, Youssoufian H, Amellal N, Rowinsky EK, Ang KK. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med. 2006 Feb 9;354(6):567-78.
Bonner JA, Buchsbaum DJ, Rogers BE, Grizzle WE, Trummell HQ, Curiel DT, Fiveash JB, Ove R, Raisch KP. Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells. Int J Radiat Oncol Biol Phys. 2004 Mar 1;58(3):950-8.
Ove R, Popple R. Sequential annealing-gradient Gamma-Knife radiosurgery optimization. Phys Med Biol. 2003 Jul 21;48(14):2071-80.
Russo SM, Ove R. Molecular targets as therapeutic strategies in the management of breast cancer. Expert Opin Ther Targets. 2003 Aug;7(4):543-57.
Popple RA, Ove R, Shen S. Tumor control probability for selective boosting of hypoxic subvolumes, including the effect of reoxygenation. Int J Radiat Oncol Biol Phys. 2002 Nov 1;54(3):921-7.