East Carolina Diabetes and Obesity Institute

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Welcome to the East Carolina Diabetes and Obesity Institute (ECDOI) at East Carolina University. The ECDOI is an interdisciplinary research institute jointly supported by the Divisions of Health Sciences and Research & Graduate Studies.

The ECDOI is well known for cutting-edge collaborative research in several fields related to disorders of metabolism, including bariatric surgery, muscle insulin signaling/glucose transport, bioenergetics/exercise physiology, and pediatric healthy weight programs.

The mission of the ECDOI is to promote and coordinate interdisciplinary basic and translational research programs in diabetes and obesity, to support the education and training of undergraduate, graduate and post-graduate students, and to foster the development of outreach prevention/treatment programs for the people of eastern North Carolina.

9th Mitochondrial Physiology School


R01 Awarded
Dr. Shaikh received a R01 entitled “Suppressing inflammation and boosting humoral immunity with n-3 PUFAs”. This award is a 5-year, $1.65 million award.
Brown & Shaikh
R15 Awarded
Dr. Brown received a R15 entitled “Treatment of cardiac reperfusion injury by optimizing the mitochondrial membrane.” This award is in collaboration with Dr. Shaikh’s lab and is a 3-year, $434,202 award to study new ways to treat mitochondria during a heart attack.
Tony 1--
Keystone Symposia Scholarship
Tony Verkerke, a Bioenergetics Ph.D. student, was awarded a Keystone Symposia scholarship for Systems Biology of Lipid Metabolism conference in Breckenridge, Colorado. A 1st year PhD student in the Funai lab, Tony presented his research entitled:“Reduced efficiency of sarcolipin-dependent respiration in myocytes from severely obese humans”. The award provided Tony with $1,700 to attend the Keystone symposia. This award was made possible through funds from NIDDK.
NIH Grant Awarded
Drs. Brown and Shaikh were recently awarded an NIH grant for $366,744. This award is from the National Heart, Lung, and Blood Institute, and was designated as a high-priority project (R56 mechanism). The title of the award is “Mitochondrial respirasomes in acute coronary syndromes”, and the grant will investigate new ways to protect the heart during a heart attack.

More news


The ECDOI is comprised of more than 40 faculty members from 17 different departments on both the main and health sciences campus. The Institute is closely aligned with the East Carolina Heart Institute (ECHI) and offers ECDOI- and/or ECHI- affiliated faculty several research support programs, access to core equipment, and opportunities to forge new collaborations through a number of interactive research forums.

To find out more

Read more about the ECDOI and all about the research happening at the ECDOI. You can also find out more about how Diabetes and Obesity impacts NC.

Contact the ECDOI

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