Division of Health SciencesThe Harriet and John Wooten Laboratory

Health Sciences Campus

Recent Publications supported by the Wooten Laboratory

Lu Q, Ding K, Frosch MP, Jones S, Wolfe M, Xia W, Lanford GW. Alzheimer's disease-linked presenilin mutation (PS1M146L) induces filamin expression and γ-secretase independent redistribution. J Alzheimers Dis. 2010; 22(1):235-245. doi: 10.3233/JAD-2010-100585.

Wu D, Raafat M, Pak E, Hammond S, Murashov AK. MicroRNA machinery responds to  peripheral nerve lesion in an injury-regulated pattern. Neuroscience. 2011 Sep 8;190:386-97. doi: 10.1016/j.neuroscience.2011.06.017.

Wu, D., Raafat, A., Pak, E., Clemens, S. and Murashov, A.K. Dicer-microRNA pathway is critical for peripheral nerve regeneration and functional recovery in vivo and regenerative axonogenesis in vitro. Exp Neurol. 2012; 233, 555-565.

Friesland A, Zhao Y, Chen YH, Wang L, Zhou H, Lu Q. Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility. Proc Natl Acad Sci U S A. 2013;110 (4):1261-6. doi: 10.1073/pnas.1116051110.

S. K. Bareiss, M. Gwaltney, K. Hernandez, T. Lee, K. L Brewer. Excitotoxic spinal cord injury induced dysesthesias are associated with enhanced intrinsic growth of sensory neurons. Neuroscience Letters, 2013; 542:113-7. PMID 23500027.

Wu D, Murashov AK. Molecular mechanisms of peripheral nerve regeneration: emerging roles of microRNAs. Front Physiol. 2013 Apr 1;4:55. doi: 10.3389/fphys.2013.00055.

Irene Hamrick, Razia Hafiz, and Doyle M. Cummings. Use of Days of the Week in a Modified Mini-Mental State Exam (M-MMSE) for Detecting Geriatric Cognitive Impairment. J Am Board Fam Med July-August 2013; 26:429-435; doi:10.3122/jabfm.2013.04.120300.

Wu D, Murashov AK. MicroRNA-431 regulates axon regeneration in mature sensory  neurons by targeting the Wnt antagonist Kremen1. Front Mol Neurosci. 2013 Oct 24;6:35. doi: 10.3389/fnmol.2013.00035.

Bareiss, S.K., Johnston, T., Jackson, J., Lu, Q., & Tran, T.D. (submitted June 2015). Exercise slows the development of early sensorimotor and cognitive symptoms in the 3xTg-ADmodel of Alzheimer's disease. Neuroscience Research.

Bareiss S, Dugan E and Brewer KL (in press). PI3K mediated activation of GSK-3beta reduces at-level primary growth responses associated with excitotoxic spinal cord injury dysesthesias. Molecular Pain (2015).

Presentations supported by the Wooten Laboratory

Johnson, T.J., Jones, K., Ortega, L., Cataldo, N., Burgess, J., Parekhm, R., Tran, T.D. The Effects of Complex Learning on Hippocampal Neurogenesis in a Mouse Model of Alzheimer's Disease. ECU Neuroscience Symposium, Greenville, NC, October, 2014.

T. Tran, Qun Lu, S.K. Bareiss. Effects of differential exercise training on hippocampal function using a triple-transgenic mouse model of Alzheimer's disease. Society for Neuroscience, San Diego, CA, November, 2013.

Conchar, I.D., Mannie, M., Lu, Q., Tran, T.D. Neurocognitive Analyses of Learning and Memory: A Longitudinal Examination of Alzheimer's Disease Utilizing the Triple Transgenic Mouse Model. Rocky Mountain Psychological Association, Denver, CO, April, 2013.

S.K Bareiss, Q. Lu, T. E. Jones, T. Tran. Effects of Exercise Frequency on Blood Biomarker Profiles in a Triple-Transgenic Mouse Model of Alzheimer's Disease. American Physical Therapy Association Combined Sections Meeting, Las Vegas, NV, February, 2013.

DeMarco, S., Clemens, S. Spinal Cord Function and Dopaminergic Modulation in a Mouse Model of Alzheimer'sDisease. ECU Neuroscience Symposium, Greenville, NC, October, 2011.

Clemens, S. Aging modified the balance of Dopamine D1 and D2 receptor expression in the spinal cord. Society for Neuroscience Abstracts, Vol. 35, 82.7 (2010).